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WormBase Tree Display for Gene: WBGene00010734

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Name Class

WBGene00010734SMapS_parentSequenceK10C8
IdentityVersion2
NameCGC_nameparn-1Person_evidenceWBPerson150
Sequence_nameK10C8.1
Molecular_nameK10C8.1
K10C8.1.1
CE39514
Other_nameCELE_K10C8.1Accession_evidenceNDBBX284605
Public_nameparn-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
221 May 2013 15:54:27WBPerson2970Name_changeCGC_nameparn-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classparn
Allele (47)
StrainWBStrain00032315
RNASeq_FPKM (74)
GO_annotation (24)
Ortholog (33)
ParalogWBGene00013265Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionparn-1 encodes a deadenylase orthologous to members of the PARN (Poly(A)-specific ribonuclease) family of nucleases; by homology, PARN-1 is predicted to catalyze mRNA poly(A) tail degradation in the 3'- to 5'-direction.Paper_evidenceWBPaper00043886
Curator_confirmedWBPerson1843
Date_last_updated23 Oct 2013 00:00:00
Automated_descriptionEnables 3'-5'-RNA exonuclease activity. Involved in RNA metabolic process and reproduction. Located in P granule. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 6 and spermatogenic failure 57. Is an ortholog of human PNLDC1 (PARN like ribonuclease domain containing exonuclease 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070024Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8609)
EFO:MONDO:0000148Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8609)
DOID:0112338Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21185)
Molecular_infoCorresponding_CDSK10C8.1
Corresponding_CDS_historyK10C8.1:wp152
Corresponding_transcriptK10C8.1.1
Other_sequenceCR04974
CRC04981_1
CBC08607_1
CRC08527_1
CR06118
CR05684
Associated_featureWBsf234711
Experimental_infoRNAi_resultWBRNAi00050503Inferred_automaticallyRNAi_primary
WBRNAi00016963Inferred_automaticallyRNAi_primary
WBRNAi00078333Inferred_automaticallyRNAi_primary
WBRNAi00034246Inferred_automaticallyRNAi_primary
WBRNAi00061852Inferred_automaticallyRNAi_primary
Expr_patternExpr12762
Expr12763
Expr1020712
Expr1034700
Expr1154214
Expr2014734
Expr2032968
Drives_constructWBCnstr00022795
WBCnstr00031186
Construct_productWBCnstr00022795
WBCnstr00031186
Microarray_results (20)
Expression_cluster (86)
Interaction (19)
Map_infoMapVPosition4.61316
PositivePositive_cloneK10C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene