WormBase Tree Display for Gene: WBGene00010706
expand all nodes | collapse all nodes | view schema
WBGene00010706 | SMap | S_parent | Sequence | K09A11 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||
Name | CGC_name | cyp-14A2 | |||||
Sequence_name | K09A11.3 | ||||||
Molecular_name | K09A11.3 | ||||||
K09A11.3.1 | |||||||
CE03474 | |||||||
Other_name | tag-190 | Person_evidence | WBPerson201 | ||||
CELE_K09A11.3 | Accession_evidence | NDB | BX284606 | ||||
Public_name | cyp-14A2 | ||||||
DB_info | Database | AceView | gene | XN886 | |||
WormQTL | gene | WBGene00010706 | |||||
WormFlux | gene | WBGene00010706 | |||||
NDB | locus_tag | CELE_K09A11.3 | |||||
Panther | gene | CAEEL|WormBase=WBGene00010706|UniProtKB=Q27505 | |||||
family | PTHR24284 | ||||||
NCBI | gene | 187184 | |||||
RefSeq | protein | NM_077803.4 | |||||
TrEMBL | UniProtAcc | Q27505 | |||||
UniProt_GCRP | UniProtAcc | Q27505 | |||||
OMIM | gene | 610670 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (3) | ||||||
Acquires_merge | WBGene00007051 | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cyp | ||||||
Allele (27) | |||||||
Strain | WBStrain00035912 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00079908 | ||||||
00079909 | |||||||
00079910 | |||||||
00118051 | |||||||
00118052 | |||||||
00118053 | |||||||
00118054 | |||||||
Ortholog (76) | |||||||
Paralog (42) | |||||||
Structured_description | Concise_description | cyp-14A2 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. | Curator_confirmed | WBPerson1843 | |||
Date_last_updated | 20 Nov 2008 00:00:00 | ||||||
Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed (2) | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (12) | ||||||
Molecular_info | Corresponding_CDS | K09A11.3 | |||||
Corresponding_transcript | K09A11.3.1 | ||||||
Other_sequence | ACC10519_1 | ||||||
Acan_isotig16510 | |||||||
Acan_isotig20860 | |||||||
PPC14875_1 | |||||||
ACC19344_1 | |||||||
ACC37757_1 | |||||||
FC540658.1 | |||||||
FC546538.1 | |||||||
FC544295.1 | |||||||
Oden_isotig28571 | |||||||
Associated_feature | WBsf238118 | ||||||
Experimental_info | RNAi_result | WBRNAi00050361 | Inferred_automatically | RNAi_primary | |||
WBRNAi00081517 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00081539 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00016860 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00034175 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00081492 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092633 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr8188 | ||||||
Expr1015820 | |||||||
Expr1154066 | |||||||
Expr2010692 | |||||||
Expr2028931 | |||||||
Drives_construct | WBCnstr00004994 | ||||||
WBCnstr00031203 | |||||||
Construct_product | WBCnstr00031203 | ||||||
Microarray_results (15) | |||||||
Expression_cluster (207) | |||||||
Interaction | WBInteraction000032180 | ||||||
WBInteraction000145443 | |||||||
WBInteraction000155641 | |||||||
WBInteraction000156225 | |||||||
WBInteraction000171003 | |||||||
WBInteraction000580718 | |||||||
Map_info | Map | X | Position | 11.1054 | Error | 0.0367 | |
Positive | Positive_clone | K09A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 5542 | |||||
4661 | |||||||
5082 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00031529 | ||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00062515 | |||||||
WBPaper00065988 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |