WormBase Tree Display for Gene: WBGene00010484
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WBGene00010484 | SMap | S_parent | Sequence | K01H12 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | dph-3 | Person_evidence | WBPerson237 | |||
Sequence_name | K01H12.1 | ||||||
Molecular_name | K01H12.1a | ||||||
K01H12.1a.1 | |||||||
CE03453 | |||||||
K01H12.1b | |||||||
CE44584 | |||||||
K01H12.1b.1 | |||||||
Other_name | CELE_K01H12.1 | Accession_evidence | NDB | BX284604 | |||
Public_name | dph-3 | ||||||
DB_info | Database (11) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | dph | ||||||
Allele (12) | |||||||
Strain | WBStrain00026526 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00007431 | ||||||
00070278 | |||||||
00070279 | |||||||
00070280 | |||||||
00070281 | |||||||
00070282 | |||||||
00070283 | |||||||
00070284 | |||||||
Ortholog (33) | |||||||
Structured_description | Concise_description | dph-3 encodes a small protein conserved in diverse eukaryotes, with a CSL motif (a probable zinc finger, sometimes found associated with the N-terminal domain of DnaJ protein); DPH-3 is probably a small subunit or ancillary protein of RNA polymerase II Elongator or of a hypothetical diphthamide synthase complex; DPH-3 is orthologous to mammalian DESR1 (diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1) and S. cerevisiae KTI11; DESR1, and probably KTI11, enables the first step in posttranslational modification of histidine to dipthamide. | Paper_evidence | WBPaper00005654 | |||
WBPaper00013055 | |||||||
WBPaper00013218 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 18 Aug 2009 00:00:00 | ||||||
Automated_description | Predicted to enable ferrous iron binding activity and iron chaperone activity. Predicted to be involved in protein histidyl modification to diphthamide and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Located in nucleus. Is an ortholog of human DPH3 (diphthamide biosynthesis 3) and DPH3P1 (diphthamide biosynthesis 3 pseudogene 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | K01H12.1a | |||||
K01H12.1b | |||||||
Corresponding_transcript | K01H12.1a.1 | ||||||
K01H12.1b.1 | |||||||
Other_sequence (56) | |||||||
Associated_feature | WBsf646248 | ||||||
WBsf228860 | |||||||
Transcription_factor | WBTranscriptionFactor000379 | ||||||
Experimental_info | RNAi_result | WBRNAi00025838 | Inferred_automatically | RNAi_primary | |||
WBRNAi00027396 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00016414 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00025839 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092977 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00115818 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00049641 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00033835 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (6) | |||||||
Drives_construct | WBCnstr00031386 | ||||||
Construct_product | WBCnstr00014067 | ||||||
WBCnstr00031386 | |||||||
Microarray_results (21) | |||||||
Expression_cluster (121) | |||||||
Interaction (49) | |||||||
Map_info (3) | |||||||
Reference | WBPaper00027309 | ||||||
WBPaper00036232 | |||||||
WBPaper00038444 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |