WormBase Tree Display for Gene: WBGene00007664

WBGene00007664 SMap: S_parent: Sequence: C18B12
  Identity: Version: 2
    Name: CGC_name: seb-3 Person_evidence: WBPerson260
      Sequence_name: C18B12.2
      Molecular_name: C18B12.2
        C18B12.2.1
        CE23557
      Other_name: secr-2 Person_evidence: WBPerson260
        CELE_C18B12.2 Accession_evidence: NDB BX284606
      Public_name: seb-3
    DB_info: Database: AceView gene XP649
        WormQTL gene WBGene00007664
        WormFlux gene WBGene00007664
        NDB locus_tag CELE_C18B12.2
        Panther gene CAEEL|WormBase=WBGene00007664|UniProtKB=G5EBF7
          family PTHR45620
        NCBI gene 181598
        RefSeq protein NM_078095.7
        TrEMBL UniProtAcc G5EBF7
        UniProt_GCRP UniProtAcc G5EBF7
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Aug 2013 09:54:03 WBPerson2970 Name_change: CGC_name: seb-3
                Other_name: secr-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: seb
    Allele (83)
    Strain: WBStrain00004042
      WBStrain00055325
    RNASeq_FPKM (74)
    GO_annotation (23)
    Ortholog (41)
    Paralog: WBGene00014035 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00015735 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002251 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002252 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009304 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00017947 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00017948 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable G protein-coupled peptide receptor activity. Involved in behavioral response to ethanol; locomotory behavior; and response to heat. Located in axon and neuronal cell body. Expressed in body wall musculature; nervous system; ray 1; and rectal gland cell. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including achalasia; inflammatory bowel disease (multiple); and type 2 diabetes mellitus. Is an ortholog of several human genes including ADCYAP1R1 (ADCYAP receptor type I); GHRHR (growth hormone releasing hormone receptor); and GIPR (gastric inhibitory polypeptide receptor). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:1574 Homo sapiens Paper_evidence: WBPaper00041356
          Curator_confirmed: WBPerson324
          Date_last_updated: 05 Jun 2019 00:00:00
    Potential_model: DOID:9351 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4271)
      DOID:8778 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12694)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4271)
      DOID:0060870 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4266)
      DOID:8577 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12694)
      DOID:1287 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4271)
      DOID:9970 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4271)
      DOID:9164 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12694)
  Models_disease_asserted: WBDOannot00000697
  Molecular_info: Corresponding_CDS: C18B12.2
    Corresponding_transcript: C18B12.2.1
    Other_sequence (18)
    Associated_feature: WBsf716895
      WBsf718783
      WBsf1008071
      WBsf1008072
      WBsf1008073
      WBsf1008074
      WBsf1024499
      WBsf1024500
      WBsf236746
      WBsf236747
  Experimental_info: RNAi_result: WBRNAi00010975 Inferred_automatically: RNAi_primary
      WBRNAi00040898 Inferred_automatically: RNAi_primary
      WBRNAi00010980 Inferred_automatically: RNAi_primary
      WBRNAi00029052 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr10550
      Expr12962
      Expr13925
      Expr1016469
      Expr1033310
      Expr1144945
      Expr2015706
      Expr2033938
    Drives_construct: WBCnstr00015756
      WBCnstr00019918
      WBCnstr00033569
      WBCnstr00038382
      WBCnstr00040425
    Construct_product: WBCnstr00019918
      WBCnstr00033569
      WBCnstr00040425
    Microarray_results (21)
    Expression_cluster (129)
    Interaction: WBInteraction000126959
      WBInteraction000155205
      WBInteraction000162595
      WBInteraction000162596
      WBInteraction000164463
      WBInteraction000167611
      WBInteraction000167710
      WBInteraction000264899
      WBInteraction000361755
      WBInteraction000560023
  Map_info: Map: X Position: 21.7956
    Positive: Positive_clone: C18B12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (18)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene