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WormBase Tree Display for Gene: WBGene00007260

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Name Class

WBGene00007260SMapS_parentSequenceC02C6
IdentityVersion3
NameCGC_nameolrn-1Person_evidenceWBPerson309
Sequence_nameC02C6.2
Molecular_nameC02C6.2a
C02C6.2a.1
CE53375
C02C6.2b
CE23514
C02C6.2b.1
Other_namensy-6Paper_evidenceWBPaper00029060
CELE_C02C6.2Accession_evidenceNDBBX284606
Public_nameolrn-1
DB_infoDatabaseWormQTLgeneWBGene00007260
WormFluxgeneWBGene00007260
NDBlocus_tagCELE_C02C6.2
PanthergeneCAEEL|WormBase=WBGene00007260|UniProtKB=Q564X8
familyPTHR36300
NCBIgene181642
RefSeqproteinNM_001373597.2
NM_001029163.8
TREEFAMTREEFAM_IDTF343081
TrEMBLUniProtAccQ564X8
Q93174
UniProt_GCRPUniProtAccQ564X8
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:47WBPerson1971EventImportedInitial conversion from CDS class of WS125
225 Jul 2007 09:59:20WBPerson2970Name_changeCGC_nameolrn-1
Other_namensy-6
302 Mar 2018 10:40:20WBPerson4025EventSplit_intoWBGene00303034
Split_intoWBGene00303034
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classolrn
Allele (146)
StrainWBStrain00022197
RNASeq_FPKM (74)
GO_annotation00081145
00081146
00081147
Ortholog (29)
Structured_descriptionConcise_descriptionolrn-1 encodes, by alternative splicing, two isoforms of a transmembrane protein required for differentiation of the AWC[ON] neuron, expression of str-2 in AWC[ON], adaptation to benzaldehyde, chemotaxis to butanone, and enhancement of chemotaxis to butanone by the presence of food; OLRN-1 is orthologous to Drosophila melanogaster RAW and Schistosoma japonicum SJCHGC05616; while OLRN-1 has orthologs in nematodes, trematodes, and arthropods, its has no obvious chordate homologs; OLRN-6 is expressed in many pharyngeal neurons and some head neurons, but is required solely in the AWC[ON] neuron for butanone enhancement; OLRN-6's function in butanone enhancement is both serotonin- and dopamine-independent, and appears to also act in chemotactic enhancement of 2,3-pentanedione and isoamyl alcohol; by orthology with RAW, OLRN-6 is predicted to inhibit JNK-1 signalling, which may in turn allow the asymmetrical AWC[ON] fate to emerge.Paper_evidenceWBPaper00029060
WBPaper00030852
Curator_confirmedWBPerson567
Date_last_updated25 Jul 2007 00:00:00
Automated_descriptionInvolved in olfactory learning. Predicted to be located in plasma membrane. Expressed in head neurons; pharyngeal cell; and rectal gland cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC02C6.2a
C02C6.2b
Corresponding_CDS_historyC02C6.2a:wp271
C02C6.2c:wp264
Corresponding_transcriptC02C6.2a.1
C02C6.2b.1
Other_sequence (11)
Associated_feature (17)
Experimental_infoRNAi_resultWBRNAi00028339Inferred_automaticallyRNAi_primary
WBRNAi00009982Inferred_automaticallyRNAi_primary
WBRNAi00039408Inferred_automaticallyRNAi_primary
Expr_patternExpr4751
Expr8020
Expr8021
Expr1020418
Expr1033132
Expr1143524
Expr2014625
Expr2032858
Drives_constructWBCnstr00012220
WBCnstr00013058
WBCnstr00013059
WBCnstr00033877
Construct_productWBCnstr00033877
Regulate_expr_clusterWBPaper00059567:olrn-1(ums9)_regulated
Microarray_results (27)
Expression_cluster (161)
InteractionWBInteraction000052792
WBInteraction000052793
WBInteraction000257638
WBInteraction000349311
WBInteraction000404163
WBInteraction000462654
Anatomy_functionWBbtf0534
WBbtf0535
WBbtf0536
WBbtf0537
WBbtf0538
WBbtf0539
WBbtf0540
WBbtf0541
WBbtf0542
Map_infoMapXPosition22.8317Error0.008909
PositivePositive_cloneC02C6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00010096
WBPaper00018960
WBPaper00029060
WBPaper00031175
WBPaper00038825
WBPaper00059567
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene