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WormBase Tree Display for Gene: WBGene00006708

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Name Class

WBGene00006708EvidenceCGC_data_submission
SMapS_parentSequenceY54G2A
IdentityVersion1
NameCGC_nameubc-13Person_evidenceWBPerson89
Sequence_nameY54G2A.31
Molecular_nameY54G2A.31
Y54G2A.31.1
CE31652
Other_nameCELE_Y54G2A.31Accession_evidenceNDBBX284604
Public_nameubc-13
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classubc
Allele (36)
RNASeq_FPKM (74)
GO_annotation (15)
Contained_in_operonCEOP4072
Ortholog (40)
Paralog (24)
Structured_descriptionConcise_descriptionubc-13 encodes an E2 ubiquitin-conjugating enzyme; by homology, UBC-13 is predicted to function in the covalent attachment of ubiquitin molecules to protein substrates, via its association with an E3 ubiquitin-protein ligase; UBC-13 physically interacts with the UEV-1 ubiquitin-conjugating enzyme variant, and like UEV-1, ubc-13 mutations result in defects in GLR-1 glutamate receptor trafficking and hence, abnormal locomotory behavior; in large-scale RNAi screens, loss of ubc-13 activity also results in embryonic lethality and reduced brood size.Paper_evidenceWBPaper00024497
WBPaper00027315
WBPaper00037956
Curator_confirmedWBPerson1843
Date_last_updated07 Feb 2011 00:00:00
Automated_descriptionContributes to ubiquitin-protein transferase activity. Involved in protein ubiquitination and regulation of protein localization to cell surface. Part of ubiquitin conjugating enzyme complex. Expressed in several structures, including intestinal cell. Is an ortholog of human UBE2N (ubiquitin conjugating enzyme E2 N) and UBE2NL (ubiquitin conjugating enzyme E2 N like (gene/pseudogene)).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY54G2A.31
Corresponding_CDS_historyY54G2A.31:wp82
Corresponding_transcriptY54G2A.31.1
Other_sequence (47)
Associated_featureWBsf995816
WBsf995817
WBsf995818
WBsf1016976
WBsf1016977
WBsf1016978
WBsf229850
WBsf229851
Experimental_infoRNAi_resultWBRNAi00082828Inferred_automaticallyRNAi_primary
WBRNAi00107653Inferred_automaticallyRNAi_primary
WBRNAi00057464Inferred_automaticallyRNAi_primary
WBRNAi00094718Inferred_automaticallyRNAi_primary
WBRNAi00107007Inferred_automaticallyRNAi_primary
WBRNAi00106926Inferred_automaticallyRNAi_primary
WBRNAi00082837Inferred_automaticallyRNAi_primary
WBRNAi00033563Inferred_automaticallyRNAi_primary
Expr_patternExpr14704
Expr1021723
Expr1032791
Expr1160895
Expr2017699
Expr2035837
Drives_constructWBCnstr00041301
Construct_productWBCnstr00041301
Microarray_results (16)
Expression_cluster (101)
Interaction (91)
Map_infoMapIVPosition-6.69587Error0.007191
PositivePositive_cloneY54G2AInferred_automaticallyFrom sequence, transcript, pseudogene data
Y94H6_148
Pseudo_map_position
Reference (16)
RemarkSequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], replaces previous (errant) sequence connection. 02/06/10 krb.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene