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WormBase Tree Display for Gene: WBGene00006702

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Name Class

WBGene00006702SMapS_parentSequenceY71G12B
IdentityVersion1
NameCGC_nameubc-3Person_evidenceWBPerson89
Sequence_nameY71G12B.15
Molecular_nameY71G12B.15a
Y71G12B.15a.1
CE38573
Y71G12B.15b
CE22885
Y71G12B.15b.1
Other_nameCELE_Y71G12B.15Accession_evidenceNDBBX284601
Public_nameubc-3
DB_infoDatabaseAceViewgene1C173
WormQTLgeneWBGene00006702
WormFluxgeneWBGene00006702
NDBlocus_tagCELE_Y71G12B.15
PanthergeneCAEEL|WormBase=WBGene00006702|UniProtKB=Q95XN7
familyPTHR24067
NCBIgene171734
RefSeqproteinNM_058481.9
NM_001306512.3
TrEMBLUniProtAccQ95XN7
W6RY98
UniProt_GCRPUniProtAccQ95XN7
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classubc
Allele (86)
StrainWBStrain00003027
RNASeq_FPKM (74)
GO_annotation00089145
00089146
00089147
00089148
00089149
00089150
00089151
Ortholog (40)
Paralog (18)
Structured_descriptionConcise_descriptionubc-3 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae and human CDC34 (OMIM:603731) which are involved in regulating protein stability during G1 and G2 cell cycle phase transitions; by homology, UBC-3 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-3 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-3 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00005337
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Is an ortholog of human CDC34 (cell division cycle 34, ubiqiutin conjugating enzyme) and UBE2R2 (ubiquitin conjugating enzyme E2 R2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY71G12B.15a
Y71G12B.15b
Corresponding_CDS_historyY71G12B.15:wp142
Corresponding_transcriptY71G12B.15a.1
Y71G12B.15b.1
Other_sequence (70)
Associated_featureWBsf643056
WBsf643057
WBsf654769
WBsf980945
WBsf982738
WBsf982739
WBsf1009241
WBsf1009242
WBsf217235
WBsf217236
Experimental_infoRNAi_resultWBRNAi00004816Inferred_automaticallyRNAi_primary
WBRNAi00116882Inferred_automaticallyRNAi_primary
WBRNAi00082840Inferred_automaticallyRNAi_primary
WBRNAi00058201Inferred_automaticallyRNAi_primary
WBRNAi00082830Inferred_automaticallyRNAi_primary
WBRNAi00094645Inferred_automaticallyRNAi_primary
Expr_patternChronogram805
Expr7109
Expr1024386
Expr1032785
Expr1161618
Expr2017713
Expr2035851
Drives_constructWBCnstr00003527
Microarray_results (21)
Expression_cluster (109)
Interaction (76)
Map_infoMapIPosition-13.3167
PositivePositive_cloneY71G12BInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkSequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], 02/06/10 krb.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
[200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-13.3727)
MethodGene