WormBase Tree Display for Gene: WBGene00006381
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WBGene00006381 | SMap | S_parent | Sequence | Y54E2A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | tac-1 | Person_evidence | WBPerson208 | |||||
Sequence_name | Y54E2A.3 | ||||||||
Molecular_name | Y54E2A.3 | ||||||||
Y54E2A.3.1 | |||||||||
CE20302 | |||||||||
Other_name | 2P40 | Accession_evidence | EMBL | AF326937 | |||||
CELE_Y54E2A.3 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | tac-1 | ||||||||
DB_info | Database | AceView | gene | 2P38 | |||||
WormQTL | gene | WBGene00006381 | |||||||
WormFlux | gene | WBGene00006381 | |||||||
NDB | locus_tag | CELE_Y54E2A.3 | |||||||
NCBI | gene | 175133 | |||||||
RefSeq | protein | NM_064658.8 | |||||||
SwissProt | UniProtAcc | G5ECG0 | |||||||
UniProt_GCRP | UniProtAcc | G5ECG0 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | tac | ||||||||
Allele (20) | |||||||||
Strain | WBStrain00037424 | ||||||||
WBStrain00007335 | |||||||||
WBStrain00007333 | |||||||||
WBStrain00050672 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (46) | |||||||||
Contained_in_operon | CEOP2648 | ||||||||
Ortholog (20) | |||||||||
Structured_description | Concise_description | tac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm. | Paper_evidence (3) | ||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Mar 2006 00:00:00 | ||||||||
Automated_description | Enables protein domain specific binding activity. Involved in several processes, including regulation of microtubule polymerization or depolymerization; sexual reproduction; and spindle organization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | Y54E2A.3 | |||||||
Corresponding_transcript | Y54E2A.3.1 | ||||||||
Other_sequence | AF326937 | ||||||||
FG620567.1 | |||||||||
Associated_feature | WBsf650765 | ||||||||
WBsf224306 | |||||||||
Experimental_info | RNAi_result (18) | ||||||||
Expr_pattern | Expr2681 | ||||||||
Expr2683 | |||||||||
Expr2684 | |||||||||
Expr2685 | |||||||||
Expr12439 | |||||||||
Expr1020108 | |||||||||
Expr1032578 | |||||||||
Expr1160809 | |||||||||
Expr2017202 | |||||||||
Expr2035338 | |||||||||
Construct_product | WBCnstr00005024 | ||||||||
WBCnstr00010900 | |||||||||
WBCnstr00015616 | |||||||||
WBCnstr00015617 | |||||||||
WBCnstr00020876 | |||||||||
WBCnstr00021102 | |||||||||
WBCnstr00022253 | |||||||||
WBCnstr00022255 | |||||||||
WBCnstr00022258 | |||||||||
WBCnstr00040176 | |||||||||
Antibody (6) | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (114) | |||||||||
Interaction (152) | |||||||||
Map_info | Map | II | Position | 23.4578 | Error | 0.010609 | |||
Positive | Positive_clone | Y54E2A | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (35) | |||||||||
Remark | Sequence connection from [Bellanger J-M, Gonczy P], 02/06/10 krb | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |