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WormBase Tree Display for Gene: WBGene00004814

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Name Class

WBGene00004814EvidenceCGC_data_submission
SMapS_parentSequenceC52D10
IdentityVersion1
NameCGC_nameskr-8Person_evidenceWBPerson322
Sequence_nameC52D10.9
Molecular_nameC52D10.9
C52D10.9.1
CE17593
Other_nameCELE_C52D10.9Accession_evidenceNDBBX284604
Public_nameskr-8
DB_infoDatabaseAceViewgene4S108
WormQTLgeneWBGene00004814
WormFluxgeneWBGene00004814
NDBlocus_tagCELE_C52D10.9
PanthergeneCAEEL|WormBase=WBGene00004814|UniProtKB=G5ECY4
familyPTHR11165
NCBIgene178495
RefSeqproteinNM_070643.6
TREEFAMTREEFAM_IDTF300142
TrEMBLUniProtAccG5ECY4
UniProt_GCRPUniProtAccG5ECY4
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classskr
Allele (18)
RNASeq_FPKM (74)
GO_annotation00012787
00012788
00012789
00012790
00012791
00113221
Ortholog (116)
Paralog (20)
Structured_descriptionConcise_descriptionskr-8 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-8 is required for is required for posterior body morphogenesis, embryonic and larval development, and cell proliferation; SKR-8 can interact with CUL-1, a C. elegans cullin homolog.Paper_evidenceWBPaper00005128
WBPaper00005129
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC52D10.9
Corresponding_transcriptC52D10.9.1
Other_sequenceCBC08783_1
CBC14567_1
CBC03418_1
Associated_featureWBsf998987
WBsf231288
WBsf231289
WBsf231290
Experimental_infoRNAi_result (24)
Expr_patternExpr2442
Expr10435
Expr1032390
Expr1146992
Expr2015855
Expr2034088
Drives_constructWBCnstr00010833
WBCnstr00015327
WBCnstr00035369
Construct_productWBCnstr00010833
WBCnstr00016566
WBCnstr00035369
Microarray_results (12)
Expression_cluster (155)
Interaction (141)
Map_infoMapIVPosition16.2359Error0.000404
PositivePositive_cloneC52D10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005129
WBPaper00006465
WBPaper00024458
WBPaper00029151
WBPaper00029221
WBPaper00033115
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene