WormBase Tree Display for Gene: WBGene00004324
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WBGene00004324 | SMap | S_parent | Sequence | F21C3 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||
Name | CGC_name | rde-2 | Person_evidence | WBPerson419 | |||
Sequence_name | F21C3.4 | ||||||
Molecular_name | F21C3.4a | ||||||
F21C3.4a.1 | |||||||
CE37005 | |||||||
F21C3.4b | |||||||
CE38174 | |||||||
F21C3.4b.1 | |||||||
Other_name | mut-8 | Paper_evidence | WBPaper00003956 | ||||
Person_evidence | WBPerson2587 | ||||||
CELE_F21C3.4 | Accession_evidence | NDB | BX284601 | ||||
Public_name | rde-2 | ||||||
DB_info | Database | WormQTL | gene | WBGene00004324 | |||
WormFlux | gene | WBGene00004324 | |||||
NDB | locus_tag | CELE_F21C3.4 | |||||
NCBI | gene | 172473 | |||||
RefSeq | protein | NM_001026227.3 | |||||
NM_001026228.4 | |||||||
TrEMBL | UniProtAcc | Q19672 | |||||
Q58AA4 | |||||||
UniProt_GCRP | UniProtAcc | Q19672 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (3) | ||||||
Acquires_merge | WBGene00003505 | ||||||
WBGene00009003 | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rde | ||||||
Allele (31) | |||||||
Strain | WBStrain00029016 | ||||||
WBStrain00040416 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00065442 | ||||||
00065443 | |||||||
00065444 | |||||||
00065445 | |||||||
00065446 | |||||||
00065447 | |||||||
00065448 | |||||||
00065449 | |||||||
00065450 | |||||||
Contained_in_operon | CEOP1384 | ||||||
Ortholog (20) | |||||||
Structured_description | Concise_description | rde-2 encodes a novel protein that is conserved in at least two other Caenorhabditis species; rde-2 is required for the functional silencing of chromosomal loci by transgenes (cosuppression) and promotes the effects of RNAi in a step after the formation of a heritable interfering agent, also affects X-chromosome nondisjunction and transposon activation; functions downstream of rde-1 in the RNAi pathway most effective against germline, but not somatically expressed, genes; RDE-2 is present predominantly in the cytosol, in complexes with MUT-7, a predicted exoribonuclease also required for RNA interference. | Paper_evidence | WBPaper00003711 | |||
WBPaper00003964 | |||||||
WBPaper00004198 | |||||||
WBPaper00005368 | |||||||
WBPaper00024699 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 22 Feb 2006 00:00:00 | ||||||
Automated_description | Involved in several processes, including meiotic chromosome segregation and regulatory ncRNA-mediated gene silencing. Located in cytosol and mutator focus. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info (5) | |||||||
Experimental_info | RNAi_result | WBRNAi00086733 | Inferred_automatically | RNAi_primary | |||
WBRNAi00003411 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00061788 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00003412 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092968 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076321 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00086728 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00031209 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116531 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00045182 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr10156 | ||||||
Expr1018003 | |||||||
Expr1032149 | |||||||
Expr1149122 | |||||||
Expr2015285 | |||||||
Expr2033519 | |||||||
Drives_construct | WBCnstr00014701 | ||||||
WBCnstr00014703 | |||||||
Construct_product | WBCnstr00014701 | ||||||
WBCnstr00014703 | |||||||
Antibody | WBAntibody00000829 | ||||||
Microarray_results (25) | |||||||
Expression_cluster (112) | |||||||
Interaction (33) | |||||||
Map_info | Map | I | Position | 1.87282 | Error | 0.000485 | |
Positive | Positive_clone | F21C3 | Inferred_automatically | From From sequence, transcript, pseudogene data | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 5087 | |||||
4953 | |||||||
5331 | |||||||
Pseudo_map_position | |||||||
Reference (51) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |