WormBase Tree Display for Gene: WBGene00004324
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WBGene00004324 | SMap | S_parent | Sequence | F21C3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | rde-2 | Person_evidence | WBPerson419 | |||||
Sequence_name | F21C3.4 | ||||||||
Molecular_name | F21C3.4a | ||||||||
F21C3.4a.1 | |||||||||
CE37005 | |||||||||
F21C3.4b | |||||||||
CE38174 | |||||||||
F21C3.4b.1 | |||||||||
Other_name (2) | |||||||||
Public_name | rde-2 | ||||||||
DB_info | Database | WormQTL | gene | WBGene00004324 | |||||
WormFlux | gene | WBGene00004324 | |||||||
NDB | locus_tag | CELE_F21C3.4 | |||||||
NCBI | gene | 172473 | |||||||
RefSeq | protein | NM_001026227.3 | |||||||
NM_001026228.4 | |||||||||
TrEMBL | UniProtAcc | Q19672 | |||||||
Q58AA4 | |||||||||
UniProt_GCRP | UniProtAcc | Q19672 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 14 Jan 2005 10:37:35 | WBPerson2970 | Event | Acquires_merge | WBGene00003505 | ||||
3 | 14 Jan 2005 10:41:26 | WBPerson2970 | Event | Acquires_merge | WBGene00009003 | ||||
Acquires_merge | WBGene00003505 | ||||||||
WBGene00009003 | |||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rde | ||||||||
Allele (31) | |||||||||
Strain | WBStrain00029016 | ||||||||
WBStrain00040416 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (9) | |||||||||
Contained_in_operon | CEOP1384 | ||||||||
Ortholog (20) | |||||||||
Structured_description | Concise_description | rde-2 encodes a novel protein that is conserved in at least two other Caenorhabditis species; rde-2 is required for the functional silencing of chromosomal loci by transgenes (cosuppression) and promotes the effects of RNAi in a step after the formation of a heritable interfering agent, also affects X-chromosome nondisjunction and transposon activation; functions downstream of rde-1 in the RNAi pathway most effective against germline, but not somatically expressed, genes; RDE-2 is present predominantly in the cytosol, in complexes with MUT-7, a predicted exoribonuclease also required for RNA interference. | Paper_evidence | WBPaper00003711 | |||||
WBPaper00003964 | |||||||||
WBPaper00004198 | |||||||||
WBPaper00005368 | |||||||||
WBPaper00024699 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPerson1843 | |||||||||
Date_last_updated | 22 Feb 2006 00:00:00 | ||||||||
Automated_description | Involved in several processes, including meiotic chromosome segregation and regulatory ncRNA-mediated gene silencing. Located in cytosol and mutator focus. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F21C3.4a | |||||||
F21C3.4b | |||||||||
Corresponding_CDS_history | F21C3.4:wp47 | ||||||||
F21C3.4:wp128 | |||||||||
Corresponding_transcript | F21C3.4a.1 | ||||||||
F21C3.4b.1 | |||||||||
Other_sequence | CBC00924_1 | ||||||||
Associated_feature | WBsf219729 | ||||||||
WBsf219730 | |||||||||
Experimental_info | RNAi_result | WBRNAi00086733 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00003411 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00061788 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00003412 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00092968 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076321 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00086728 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00031209 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00116531 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00045182 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr10156 | ||||||||
Expr1018003 | |||||||||
Expr1032149 | |||||||||
Expr1149122 | |||||||||
Expr2015285 | |||||||||
Expr2033519 | |||||||||
Drives_construct | WBCnstr00014701 | ||||||||
WBCnstr00014703 | |||||||||
Construct_product | WBCnstr00014701 | ||||||||
WBCnstr00014703 | |||||||||
Antibody | WBAntibody00000829 | ||||||||
Microarray_results (25) | |||||||||
Expression_cluster (112) | |||||||||
Interaction (33) | |||||||||
Map_info | Map | I | Position | 1.87282 | Error | 0.000485 | |||
Positive | Positive_clone | F21C3 | Inferred_automatically | From From sequence, transcript, pseudogene data | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 5087 | |||||||
4953 | |||||||||
5331 | |||||||||
Pseudo_map_position | |||||||||
Reference (51) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |