WormBase Tree Display for Gene: WBGene00004274
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WBGene00004274 | SMap | S_parent | Sequence | F53G12 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rab | ||||||
Allele (49) | |||||||
Strain | WBStrain00040386 | ||||||
WBStrain00040387 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (34) | |||||||
Contained_in_operon | CEOP1957 | ||||||
Ortholog (43) | |||||||
Paralog (32) | |||||||
Structured_description | Concise_description | rab-11.1 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; RAB-11.1 activity is required for completion of the final stages of cytokinesis during early embryogenesis and for efficient uptake of yolk proteins during oocyte development; RAB-11.1 is also required for normal peripheral localization of nuclei in the synctial germ cell in the ovary and for regulated secretion of CAV-1-containing cortical granules following fertilization; RAB-11.1 localizes to recycling endosomes and to cortical granules. | Paper_evidence | WBPaper00003831 | |||
WBPaper00004697 | |||||||
WBPaper00027018 | |||||||
WBPaper00032152 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 Feb 2011 00:00:00 | ||||||
Automated_description | Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including eggshell formation; membrane addition at site of mitotic cytokinesis; and vesicle-mediated transport. Located in Golgi trans cisterna membrane; cortical granule; and recycling endosome. Expressed in gonad. Is an ortholog of human RAB11A (RAB11A, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F53G12.1 | |||||
Corresponding_transcript | F53G12.1.1 | ||||||
Other_sequence (124) | |||||||
Associated_feature | WBsf648892 | ||||||
WBsf663857 | |||||||
WBsf663858 | |||||||
WBsf218867 | |||||||
WBsf218868 | |||||||
WBsf218869 | |||||||
WBsf218870 | |||||||
WBsf218871 | |||||||
Experimental_info | RNAi_result (31) | ||||||
Expr_pattern | Expr4018 | ||||||
Expr4949 | |||||||
Expr8340 | |||||||
Expr8341 | |||||||
Expr8956 | |||||||
Expr1022979 | |||||||
Expr1032113 | |||||||
Expr1151979 | |||||||
Expr2015214 | |||||||
Expr2033448 | |||||||
Drives_construct | WBCnstr00012362 | ||||||
Construct_product (24) | |||||||
Antibody | WBAntibody00001208 | ||||||
WBAntibody00001396 | |||||||
WBAntibody00001957 | |||||||
Microarray_results (23) | |||||||
Expression_cluster (146) | |||||||
Interaction (110) | |||||||
Map_info | Map | I | Position | -19.8403 | Error | 0.203444 | |
Positive | Positive_clone | F53G12 | Inferred_automatically (2) | ||||
Mapping_data | Multi_point | 5490 | |||||
Pseudo_map_position | |||||||
Reference (42) | |||||||
Remark | Sequence connection from [Kuwabara PE] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |