WormBase Tree Display for Gene: WBGene00004095
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| WBGene00004095 | Evidence | Paper_evidence | WBPaper00005585 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F52C9 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | pqe-1 | Person_evidence | WBPerson242 | |||||
| Sequence_name | F52C9.8 | ||||||||
| Molecular_name (18) | |||||||||
| Other_name | CELE_F52C9.8 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | pqe-1 | ||||||||
| DB_info | Database | AceView | gene | 3G411 | |||||
| WormQTL | gene | WBGene00004095 | |||||||
| WormFlux | gene | WBGene00004095 | |||||||
| NDB | locus_tag | CELE_F52C9.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004095|UniProtKB=Q10124 | |||||||
| family | PTHR12801 | ||||||||
| NCBI | gene | 175731 | |||||||
| RefSeq | protein | NM_065734.9 | |||||||
| NM_001047389.4 | |||||||||
| NM_171120.6 | |||||||||
| NM_001382869.2 | |||||||||
| NM_065735.7 | |||||||||
| SwissProt | UniProtAcc | Q10124 | |||||||
| TREEFAM | TREEFAM_ID | TF350172 | |||||||
| UniProt_GCRP | UniProtAcc | Q10124 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pqe | ||||||||
| Allele (166) | |||||||||
| Strain | WBStrain00003715 | ||||||||
| WBStrain00032306 | |||||||||
| WBStrain00008294 | |||||||||
| WBStrain00054750 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP3284 | ||||||||
| Ortholog (72) | |||||||||
| Paralog | WBGene00012465 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00013244 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00015462 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021653 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | pqe-1 produces through alternative splicing, proteins that contain a glutamineproline-rich domain and/or an exonuclease domain; the exonuclease domain is most similar to GOR proteins found in humans and gorillas and to the Saccharomyces cerevisiae Rex3p RNA exonuclease; in a C. elegans model for huntingtin polyglutamine neurotoxicity, pqe-1 proteins protect the ASH sensory neurons from polyglutamine (PolyQ)-induced neurodegeneration. | Paper_evidence | WBPaper00005585 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 26 Mar 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable exonuclease activity. Involved in negative regulation of gene expression. Located in nucleus. Expressed in ventral cord neurons. Is an ortholog of human REXO1 (RNA exonuclease 1 homolog). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F52C9.8a | |||||||
| F52C9.8b | |||||||||
| F52C9.8c | |||||||||
| F52C9.8f | |||||||||
| F52C9.8g | |||||||||
| Corresponding_CDS_history | F52C9.8b:wp93 | ||||||||
| F52C9.8d:wp270 | |||||||||
| F52C9.8e:wp270 | |||||||||
| Corresponding_transcript | F52C9.8a.1 | ||||||||
| F52C9.8a.2 | |||||||||
| F52C9.8a.3 | |||||||||
| F52C9.8a.4 | |||||||||
| F52C9.8b.1 | |||||||||
| F52C9.8c.1 | |||||||||
| F52C9.8f.1 | |||||||||
| F52C9.8g.1 | |||||||||
| Other_sequence (13) | |||||||||
| Associated_feature (17) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00006838 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00005110 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062261 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047956 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047957 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015387 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047955 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032599 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001179 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00103376 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr6136 | ||||||||
| Expr8163 | |||||||||
| Expr11463 | |||||||||
| Expr1026994 | |||||||||
| Expr1031979 | |||||||||
| Expr1151776 | |||||||||
| Expr2015029 | |||||||||
| Expr2033264 | |||||||||
| Drives_construct | WBCnstr00004150 | ||||||||
| WBCnstr00019038 | |||||||||
| WBCnstr00035701 | |||||||||
| Construct_product | WBCnstr00013151 | ||||||||
| WBCnstr00035701 | |||||||||
| Antibody | WBAntibody00000578 | ||||||||
| WBAntibody00000579 | |||||||||
| WBAntibody00000580 | |||||||||
| Microarray_results (62) | |||||||||
| Expression_cluster (136) | |||||||||
| Interaction (22) | |||||||||
| Anatomy_function | WBbtf0189 | ||||||||
| WBbtf0659 | |||||||||
| WBbtf0660 | |||||||||
| WBbtf0661 | |||||||||
| Map_info | Map | III | Position | -1.82825 | Error | 0.00766 | |||
| Positive | Positive_clone | F52C9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Pos_neg_data | 10679 | |||||||
| Reference (19) | |||||||||
| Remark | data extracted from PMID12486229 | ||||||||
| Postitive method is cosmid rescue | |||||||||
| Method | Gene |
