WormBase Tree Display for Gene: WBGene00004063
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| WBGene00004063 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pmr-1 | |||||||
| Sequence_name | ZK256.1 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | pmr1 | Accession_evidence | EMBL | AJ303081 | |||||
| AJ303082 | |||||||||
| CELE_ZK256.1 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | pmr-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info (9) | |||||||||
| Disease_info | Potential_model | DOID:0050429 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13211) | ||||
| Disease_relevance | C. elegans is an effective model system to study heat-related pathologies like heat stroke; in elegans, a small heat shock protein (sHSP), HSP-16.1 has a protective effect against heat-induced necrosis; HSP-16.1 localizes to the golgi and functions together with the PMR-1/PMR1 Ca2+ and Mn2+ transporting ATPase, and NUCB-1/Nucleobindin1, a golgi-located calcium-buffering protein, to maintain calcium homeostasis, under heat stroke; overexpression of pmr-1/PMR1 is sufficient to promote survival after heat stroke, bypassing both HSF-1 and HSP-16.1, indicating that PMR-1/PMR1 functions downstream of both these genes. | Homo sapiens | Paper_evidence | WBPaper00041564 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 29 May 2013 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK256.1a | |||||||
| ZK256.1b | |||||||||
| ZK256.1c | |||||||||
| Corresponding_CDS_history | ZK256.1:wp114 | ||||||||
| ZK256.1a:wp49 | |||||||||
| ZK256.1b:wp77 | |||||||||
| Corresponding_transcript (5) | |||||||||
| Other_sequence (75) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00059919 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00038238 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116858 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059917 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059303 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059920 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00086175 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059921 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1105 | ||||||||
| Expr3187 | |||||||||
| Expr7200 | |||||||||
| Expr1017781 | |||||||||
| Expr1031961 | |||||||||
| Expr1162731 | |||||||||
| Expr2014977 | |||||||||
| Expr2033212 | |||||||||
| Drives_construct | WBCnstr00003233 | ||||||||
| WBCnstr00011207 | |||||||||
| Construct_product | WBCnstr00011207 | ||||||||
| Antibody | WBAntibody00000363 | ||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (114) | |||||||||
| Interaction (69) | |||||||||
| Map_info | Map | I | Position | 17.0977 | Error | 0.064933 | |||
| Positive | Positive_clone | ZK256 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5071 | |||||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Sequence connection from [Van Baelenk, Wuytack, F] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
