WormBase Tree Display for Gene: WBGene00004048
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WBGene00004048 | Evidence | CGC_data_submission | |||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | K04B12 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | plx | ||||||
Allele (139) | |||||||
Strain | WBStrain00029146 | ||||||
WBStrain00029147 | |||||||
WBStrain00029148 | |||||||
WBStrain00029149 | |||||||
WBStrain00030125 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (30) | |||||||
Ortholog (31) | |||||||
Paralog | WBGene00004047 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | plx-2 encodes one of two C. elegans plexins, conserved transmembrane proteins that function as semaphorin receptors in both vertebrates and invertebrates; plx-2 activity is essential for proper male tail and epidermal morphogenesis and for normal axon guidance in a select group of neurons, including SDQL; genetic analyses indicate that plx-2 functions with mab-20/semaphorin-2a, efn-4/ephrin-4, and unc-129/TGF-beta to regulate male tail morphogenesis and with mab-20 and lad-2/L1CAM to mediate axon guidance; PLX-2 can bind MAB-20 and this interaction is enhanced in the presence of LAD-2; PLX-2::GFP reporters are expressed in a subset of neurons and epidermal cells, as well as a subset (1, 3, 5, and 7) of male sensory ray cell clusters. | Paper_evidence | WBPaper00006490 | |||
WBPaper00029396 | |||||||
WBPaper00031430 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 23 Jul 2008 00:00:00 | ||||||
Automated_description | Enables semaphorin receptor activity. Involved in several processes, including axonal fasciculation; nematode larval development; and nematode male tail tip morphogenesis. Located in cell leading edge and cell surface. Expressed in several structures, including P3/4L; P9/10L; P9/10R; neuroblasts; and ray structural cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed (2) | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | K04B12.1 | |||||
Corresponding_CDS_history | K04B12.1:wp92 | ||||||
K04B12.1:wp109 | |||||||
K04B12.1:wp180 | |||||||
K04B12.1:wp274 | |||||||
Corresponding_transcript | K04B12.1.1 | ||||||
Other_sequence | Dviv_isotig22187 | ||||||
FC552303.1 | |||||||
ACC17590_1 | |||||||
FC551755.1 | |||||||
JI164274.1 | |||||||
Acan_isotig12889 | |||||||
Dviv_isotig33737 | |||||||
Dviv_isotig33915 | |||||||
Oden_isotig23212 | |||||||
Associated_feature (17) | |||||||
Experimental_info | RNAi_result | WBRNAi00065915 | Inferred_automatically | RNAi_primary | |||
WBRNAi00016577 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00049879 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00000986 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr2929 | ||||||
Expr4682 | |||||||
Expr10005 | |||||||
Expr1023808 | |||||||
Expr1031948 | |||||||
Expr1153584 | |||||||
Expr1200099 | |||||||
Expr2014968 | |||||||
Expr2033203 | |||||||
Drives_construct (15) | |||||||
Construct_product | WBCnstr00000486 | ||||||
WBCnstr00035722 | |||||||
Microarray_results (21) | |||||||
Expression_cluster (209) | |||||||
Interaction (29) | |||||||
WBProcess | WBbiopr:00000025 | ||||||
Map_info | Map | II | Position | 22.9962 | Error | 0.007199 | |
Positive | Positive_clone | K04B12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4590 | |||||
Pseudo_map_position | |||||||
Reference (148) | |||||||
Remark | Sequence connection from [Takagi S] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
[wm99ab616], [wm2001p535], and [jwm2000ab65] used cep-1 as an unapproved name for CGC plx-2 (K04B12.1). The CGC cep-1 (F52B5.5) is a p53 homolog | |||||||
Method | Gene |