WormBase Tree Display for Gene: WBGene00003917
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WBGene00003917 | SMap | S_parent | Sequence | F58B6 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | par-2 | Person_evidence | WBPerson314 | |||
Sequence_name | F58B6.3 | ||||||
Molecular_name (19) | |||||||
Other_name | CELE_F58B6.3 | Accession_evidence | NDB | BX284603 | |||
Public_name | par-2 | ||||||
DB_info | Database | AceView | gene | 3C183 | |||
WormQTL | gene | WBGene00003917 | |||||
WormFlux | gene | WBGene00003917 | |||||
NDB | locus_tag | CELE_F58B6.3 | |||||
Panther | gene | CAEEL|WormBase=WBGene00003917|UniProtKB=Q965F9 | |||||
family | PTHR44080 | ||||||
NCBI | gene | 175275 | |||||
RefSeq | protein | NM_001420607.1 | |||||
NM_001027459.7 | |||||||
NM_001420609.1 | |||||||
NM_001420606.1 | |||||||
NM_001381725.1 | |||||||
TrEMBL | UniProtAcc | A0A8S4SQT8 | |||||
A0A8S4SL65 | |||||||
A0A8S4SK97 | |||||||
H1ZUX3 | |||||||
Q965F9 | |||||||
UniProt_GCRP | UniProtAcc | A0A8S4SQT8 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Split_into | WBGene00306125 | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | par | ||||||
Allele (329) | |||||||
Legacy_information | it46ts mat : homozygous hermaphrodites produce 90% (16x) to 99% (25x) arrested embryos escapers sterile; abnormal early cleavages defective P granule localization. ES3 (progeny). NA4 (it5ts : weaker phenotype e2030 : grandchildless). | ||||||
See also e2030 | |||||||
[C.elegansII] it46ts,mat : homozygous hermaphrodites produce 90% (16C) to 99% (25C) arrested embryos, escapers sterile; abnormal early cleavages, both spindles transverse at 2nd cleavage (failure of P1 rotation), defective P granule localization. ES3 (progeny). OA7: it5ts (weaker phenotype), e2030 (Mes, grandchildless),it87 (weak),jb2, etc. All ts; temp shift indicates not needed after 2nd cleavage. Cloned: encodes predicted novel protein. Antibody staining indicates specific asymmetric cortical localizations in early blastomeres. [Cheng et al. 1995; KK] | |||||||
Strain (17) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (26) | |||||||
Contained_in_operon | CEOP3056 | ||||||
Ortholog (22) | |||||||
Structured_description | Concise_description | par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3. | Paper_evidence | WBPaper00005115 | |||
WBPaper00005317 | |||||||
WBPaper00005405 | |||||||
WBPaper00005575 | |||||||
WBPaper00005735 | |||||||
WBPaper00005778 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables microtubule binding activity; phosphatidylinositol phosphate binding activity; and protein kinase binding activity. Involved in asymmetric cell division; asymmetric protein localization involved in cell fate determination; and establishment of mitotic spindle orientation. Located in P granule; posterior cell cortex; and protein-containing complex. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F58B6.3a | |||||
F58B6.3b | |||||||
F58B6.3c | |||||||
F58B6.3d | |||||||
F58B6.3e | |||||||
Corresponding_CDS_history | F58B6.3:wp19 | ||||||
F58B6.3a:wp229 | |||||||
F58B6.3a:wp283 | |||||||
F58B6.3b:wp150 | |||||||
Corresponding_transcript | F58B6.3a.1 | ||||||
F58B6.3b.1 | |||||||
F58B6.3c.1 | |||||||
F58B6.3d.1 | |||||||
F58B6.3e.1 | |||||||
F58B6.3e.2 | |||||||
F58B6.3e.3 | |||||||
F58B6.3e.4 | |||||||
F58B6.3e.5 | |||||||
Other_sequence | CR05646 | ||||||
CRC02017_1 | |||||||
MPC00003_1 | |||||||
Associated_feature (14) | |||||||
Experimental_info (9) | |||||||
Map_info | Map | III | Position | -23.7021 | Error | 0.225136 | |
Well_ordered | |||||||
Positive | Positive_clone | F58B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Y11F11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | 2_point | 2720 | |||||
2721 | |||||||
4699 | |||||||
Multi_point (11) | |||||||
Landmark_gene | |||||||
Reference (312) | |||||||
Method | Gene |