WormBase Tree Display for Gene: WBGene00003907
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| WBGene00003907 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C52B9 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | paf-2 | Person_evidence | WBPerson1105 | |||||
| Sequence_name | C52B9.7 | ||||||||
| Molecular_name | C52B9.7a | ||||||||
| C52B9.7a.1 | |||||||||
| CE30264 | |||||||||
| C52B9.7b | |||||||||
| CE30265 | |||||||||
| C52B9.7a.2 | |||||||||
| C52B9.7b.1 | |||||||||
| Other_name | CELE_C52B9.7 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | paf-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | paf | ||||||||
| Allele (121) | |||||||||
| Strain | WBStrain00040614 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00003906 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | paf-2 encodes one of two C. elegans homologs of mammalian Type II platelet-activating factor-acetylhydrolase (PAF-AH); paf-2 activity is essential for embryonic morphogenesis, specifically for the proper organization, alignment, and adhesion of hypodermal cells during embryonic enclosure; a paf-2::GFP reporter fusion is expressed in hypodermal cells and in the intestine, beginning of embryonic elongation. | Paper_evidence | WBPaper00024453 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 27 Nov 2007 00:00:00 | ||||||||
| Automated_description | Enables 1-alkyl-2-acetylglycerophosphocholine esterase activity. Involved in lipid catabolic process and morphogenesis of embryonic epithelium. Predicted to be located in cytosol and endoplasmic reticulum membrane. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and glomerulonephritis (multiple). Is an ortholog of human PAFAH2 (platelet activating factor acetylhydrolase 2) and PLA2G7 (phospholipase A2 group VII). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (23) | ||||||||
| Molecular_info | Corresponding_CDS | C52B9.7a | |||||||
| C52B9.7b | |||||||||
| Corresponding_transcript | C52B9.7a.1 | ||||||||
| C52B9.7a.2 | |||||||||
| C52B9.7b.1 | |||||||||
| Other_sequence (18) | |||||||||
| Associated_feature | WBsf653900 | ||||||||
| WBsf670407 | |||||||||
| WBsf670408 | |||||||||
| WBsf1004897 | |||||||||
| WBsf1004898 | |||||||||
| WBsf1022762 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00114800 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00012298 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038529 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00043017 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001476 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3074 | ||||||||
| Expr1026873 | |||||||||
| Expr1031843 | |||||||||
| Expr1146981 | |||||||||
| Expr2014682 | |||||||||
| Expr2032915 | |||||||||
| Drives_construct | WBCnstr00011116 | ||||||||
| WBCnstr00035803 | |||||||||
| Construct_product | WBCnstr00035803 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (142) | |||||||||
| Interaction (25) | |||||||||
| Map_info | Map | X | Position | -7.79555 | Error | 0.001211 | |||
| Positive | Positive_clone | C52B9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5504 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00011883 | ||||||||
| WBPaper00011941 | |||||||||
| WBPaper00019637 | |||||||||
| WBPaper00024453 | |||||||||
| WBPaper00029387 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062388 | |||||||||
| Remark | Sequence connection from [Arai H, Inoue T] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
