WormBase Tree Display for Gene: WBGene00003474
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WBGene00003474 | SMap | S_parent | Sequence | T08G5 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name (5) | |||||||||
DB_info | Database | AceView | gene | 5O498 | |||||
WormQTL | gene | WBGene00003474 | |||||||
WormFlux | gene | WBGene00003474 | |||||||
NDB | locus_tag | CELE_T08G5.10 | |||||||
NCBI | gene | 179899 | |||||||
RefSeq | protein | NM_074081.9 | |||||||
SwissProt | UniProtAcc | P17512 | |||||||
UniProt_GCRP | UniProtAcc | P17512 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | mtl | ||||||||
Allele (15) | |||||||||
Legacy_information | [C.elegansII] NMK. Encodes 63 aa metallothionein; accumulates after exposure to CdCl2. mtl-1:lacZ expressed in intestine after cadmium treatment or heat shock. [Freedman et al. 1993] | ||||||||
Strain | WBStrain00005079 | ||||||||
WBStrain00005080 | |||||||||
WBStrain00005081 | |||||||||
WBStrain00005101 | |||||||||
WBStrain00040877 | |||||||||
WBStrain00035525 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00039557 | ||||||||
00039558 | |||||||||
00106045 | |||||||||
00106046 | |||||||||
00106267 | |||||||||
00106268 | |||||||||
Ortholog | WBGene00027389 | Caenorhabditis briggsae | From_analysis | OrthoMCL | |||||
OMA | |||||||||
WBGene00027390 | Caenorhabditis briggsae | From_analysis | OrthoMCL | ||||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
WBGene00151369 | Caenorhabditis brenneri | From_analysis | OMA | ||||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
WBGene00271681 | Caenorhabditis briggsae | From_analysis | WormBase-Compara | ||||||
FL83_06429 | Caenorhabditis latens | From_analysis | WormBase-Compara | ||||||
GCK72_020394 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||||
chrV_pilon.g16404 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00057046 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | mtl-2 encodes one of two C. elegans metallothioneins, small, cysteine-rich, metal-binding proteins; MTL-2 functions in metal detoxification and homeostasis and stress adaptation; in addition, mtl-2 plays a role in regulating growth and fertility; mtl-2 expression is induced in larval and adult intestinal cells following exposure to cadmium or heat shock; MTL-2 intestinal expression is dependent upon ELT-2, an intestine-specific GATA-type transcription factor; mtl-2 is downregulated by DAF-16 in daf-2 mutants. | Paper_evidence | WBPaper00001688 | |||||
WBPaper00003700 | |||||||||
WBPaper00004299 | |||||||||
WBPaper00004381 | |||||||||
WBPaper00005295 | |||||||||
WBPaper00005976 | |||||||||
WBPaper00028866 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 07 May 2007 00:00:00 | ||||||||
Automated_description | Enables cadmium ion binding activity and zinc ion binding activity. Involved in response to cadmium ion and response to heat. Expressed in intestinal cell and intestine. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T08G5.10 | |||||||
Corresponding_transcript | T08G5.10.1 | ||||||||
Other_sequence | CBC00932_1 | ||||||||
CBC01514_2 | |||||||||
FD517649.1 | |||||||||
CBC01514_1 | |||||||||
CJC01860_1 | |||||||||
CSC00487_1 | |||||||||
FD517704.1 | |||||||||
Associated_feature | WBsf653359 | ||||||||
WBsf919637 | |||||||||
WBsf919638 | |||||||||
WBsf982357 | |||||||||
WBsf982358 | |||||||||
WBsf234895 | |||||||||
Experimental_info | RNAi_result (11) | ||||||||
Expr_pattern | Expr1380 | ||||||||
Expr1509 | |||||||||
Expr3079 | |||||||||
Expr1020789 | |||||||||
Expr1156496 | |||||||||
Expr2013808 | |||||||||
Expr2032048 | |||||||||
Drives_construct (15) | |||||||||
Construct_product | WBCnstr00007972 | ||||||||
WBCnstr00007973 | |||||||||
WBCnstr00011119 | |||||||||
WBCnstr00036093 | |||||||||
Microarray_results (19) | |||||||||
Expression_cluster (257) | |||||||||
Interaction (39) | |||||||||
WBProcess (4) | |||||||||
Map_info | Map | V | Position | 6.07164 | Error | 0.009738 | |||
Positive | Positive_clone | CR#MT2 | |||||||
T08G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4288 | |||||||
4500 | |||||||||
Pseudo_map_position | |||||||||
Reference (74) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |