WormBase Tree Display for Gene: WBGene00003293
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| WBGene00003293 | Evidence | Paper_evidence | WBPaper00004928 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | Y48G9A | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | mir-65 | Person_evidence | WBPerson18 | |||||
| Sequence_name | Y48G9A.14 | ||||||||
| Molecular_name | Y48G9A.14 | ||||||||
| Y48G9A.14a | |||||||||
| Y48G9A.14b | |||||||||
| Other_name | cel-mir-65 | Remark | miRBase V21 import | ||||||
| Cel-Mir-65-P1 | Remark | MirGeneDB 2.1 import | |||||||
| CELE_Y48G9A.14 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | mir-65 | ||||||||
| DB_info | Database | miRBase | acc | MI0000036 | |||||
| SignaLink | mirna | cel-mir-65 | |||||||
| MirGeneDB | cel | Cel-Mir-65-P1 | |||||||
| NDB | locus_tag | CELE_Y48G9A.14 | |||||||
| NCBI | gene | 260238 | |||||||
| RefSeq | protein | NR_000278.2 | |||||||
| RNAcentral | URSid | URS00000C1065 | |||||||
| URS0000508158 | |||||||||
| URS00005FF70E | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001265 | |||||||
| Gene_class | mir | ||||||||
| Allele | WBVar01500082 | ||||||||
| WBVar02146676 | |||||||||
| WBVar00252324 | |||||||||
| WBVar01498832 | |||||||||
| WBVar00090954 | |||||||||
| WBVar00323169 | |||||||||
| WBVar02151754 | |||||||||
| WBVar00808118 | |||||||||
| WBVar00808119 | |||||||||
| Strain | WBStrain00027559 | ||||||||
| In_cluster | MIR-65 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| Structured_description | Concise_description | mir-65 encodes a microRNA (miRNA), a small noncoding RNA that is likely involved in post-transcriptional regulation of gene expression; miR-65 is expressed at high levels during all developmental stages and in glp-4 mutant hermaphrodites lacking a germline; miR-65 is also detected in him-8 mutants, starved L1 larvae, and dauer larvae; miR-65 does not appear to have orthologs in other species, and the targets of miR-65 are not yet known; miR-65 is part of a miRNA gene cluster that also contains mir-64 and mir-66. | Paper_evidence | WBPaper00004927 | |||||
| WBPaper00005825 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Used to study Parkinson's disease. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:14330 | Homo sapiens | Paper_evidence | WBPaper00035654 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 06 Jan 2014 00:00:00 | ||||||||
| Disease_relevance | mir-65 is a small non-protein coding RNA; microRNA expression profiling studies in an elegans transgenic model of Parkinson''s disease, where A53T alpha-synuclein is overexpressed, indicate that elegans mir-65 and mir-64 are co-underexpressed, as they are, also in a cat-1 (vesicular catecholamine transporter) mutant. | Homo sapiens | Paper_evidence | WBPaper00035654 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 06 Jan 2014 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00000264 | ||||||||
| Molecular_info | Corresponding_transcript | Y48G9A.14 | |||||||
| Y48G9A.14a | |||||||||
| Y48G9A.14b | |||||||||
| Experimental_info | Expr_pattern | Expr2491 | |||||||
| Regulate_expr_cluster | WBPaper00064999:miR-229-64-65-66_downregulated | ||||||||
| WBPaper00064999:miR-229-64-65-66_upregulated | |||||||||
| Expression_cluster (22) | |||||||||
| Interaction | WBInteraction000009105 | ||||||||
| WBInteraction000536195 | |||||||||
| WBInteraction000536196 | |||||||||
| WBInteraction000536197 | |||||||||
| WBInteraction000536202 | |||||||||
| WBInteraction000536203 | |||||||||
| WBInteraction000542246 | |||||||||
| WBInteraction000536193 | |||||||||
| Map_info | Positive | Inside_rearr | nDf63 | ||||||
| Positive_clone | Y48G9A | Inferred_automatically | From CDS info | ||||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Pos_neg_data | 10938 | |||||||
| Interpolated_map_position | III | -15.0631 | |||||||
| Reference | WBPaper00004927 | ||||||||
| WBPaper00005825 | |||||||||
| WBPaper00024441 | |||||||||
| WBPaper00031335 | |||||||||
| WBPaper00032187 | |||||||||
| WBPaper00033207 | |||||||||
| WBPaper00035664 | |||||||||
| WBPaper00037982 | |||||||||
| WBPaper00064999 | |||||||||
| Method | Gene |
