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WormBase Tree Display for Gene: WBGene00002241

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Name Class

WBGene00002241SMapS_parentSequenceF10C2
IdentityVersion1
NameCGC_namekup-1Person_evidenceWBPerson71
Sequence_nameF10C2.2
Molecular_nameF10C2.2
F10C2.2.1
CE09306
Other_name (2)
Public_namekup-1
DB_infoDatabaseAceViewgene5M514
WormQTLgeneWBGene00002241
WormFluxgeneWBGene00002241
NDBlocus_tagCELE_F10C2.2
NCBIgene179651
RefSeqproteinNM_001392622.1
SwissProtUniProtAccP34705
UniProt_GCRPUniProtAccP34705
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkup
Allele (99)
Legacy_information[C.elegansII] NMK. Upstream in operon with kin-13. Encodes predicted 385 aa novel protein. Antibody stains nuclei of most cells. [Zorio et al. 1994; CR]
StrainWBStrain00035751
RNASeq_FPKM (74)
Contained_in_operonCEOP5312
Ortholog (27)
Structured_descriptionConcise_descriptionkup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00001950
WBPaper00005493
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnriched in several structures, including AVK; MSaapaapa; accessory cell; anterior arcade cell; and g2 based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and gld-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF10C2.2
Corresponding_transcriptF10C2.2.1
Other_sequence (42)
Associated_feature (30)
Experimental_infoRNAi_resultWBRNAi00044221Inferred_automaticallyRNAi_primary
WBRNAi00013038Inferred_automaticallyRNAi_primary
WBRNAi00085043Inferred_automaticallyRNAi_primary
Expr_patternExpr12857
Expr1021564
Expr1031316
Expr1148182
Expr2012983
Expr2031215
Drives_constructWBCnstr00022908
Microarray_results (20)
Expression_cluster (139)
InteractionWBInteraction000227835
WBInteraction000396019
WBInteraction000435475
WBInteraction000574965
WBInteraction000576308
Map_infoMapVPosition3.60848Error0.003861
PositivePositive_cloneF10C2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4470
4586
Pseudo_map_position
Reference (7)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene