WormBase Tree Display for Gene: WBGene00002051
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WBGene00002051 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | ifa-3 | Person_evidence | WBPerson105 | |||||
WBPerson293 | |||||||||
Sequence_name | F52E10.5 | ||||||||
Molecular_name | F52E10.5 | ||||||||
F52E10.5.1 | |||||||||
CE34875 | |||||||||
Other_name | Cel IF A3 | Accession_evidence | EMBL | X70831 | |||||
CelIF a3 | |||||||||
A3 | Paper_evidence | WBPaper00006137 | |||||||
CELE_F52E10.5 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | ifa-3 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ifa | ||||||||
Allele (42) | |||||||||
Strain | WBStrain00036840 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (12) | |||||||||
Ortholog (69) | |||||||||
Paralog (12) | |||||||||
Structured_description | Concise_description | ifa-3 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-3 is required for survival past early larval stages, correct positioning of excretory canals and body muscles, attachment of cuticle to hypodermis, and locomotion; IFA-3 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-3 is expressed in embryonic and larval, but not adult, hypodermis. | Paper_evidence | WBPaper00001981 | |||||
WBPaper00004761 | |||||||||
WBPaper00006137 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in nuclear envelope and nuclear lamina. Expressed in hypodermis and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
Molecular_info | Corresponding_CDS | F52E10.5 | |||||||
Corresponding_CDS_history | F52E10.5:wp83 | ||||||||
F52E10.5:wp102 | |||||||||
F52E10.5:wp106 | |||||||||
Corresponding_transcript | F52E10.5.1 | ||||||||
Other_sequence (33) | |||||||||
Associated_feature | WBsf718810 | ||||||||
WBsf238387 | |||||||||
WBsf238388 | |||||||||
Experimental_info (7) | |||||||||
Map_info | Map | X | Position | 23.7263 | Error | 0.00238 | |||
Positive | Positive_clone | F52E10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (15) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |