WormBase Tree Display for Gene: WBGene00002035
expand all nodes | collapse all nodes | view schema
| WBGene00002035 | SMap | S_parent | Sequence | F29D10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hum-1 | |||||||
| Sequence_name | F29D10.4 | ||||||||
| Molecular_name | F29D10.4 | ||||||||
| F29D10.4.1 | |||||||||
| CE05763 | |||||||||
| Other_name | CELE_F29D10.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | hum-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hum | ||||||||
| Allele (45) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes predicted unconventional myosin heavy chain, class I. [DU] | ||||||||
| Strain | WBStrain00003321 | ||||||||
| WBStrain00031531 | |||||||||
| WBStrain00031252 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (38) | |||||||||
| Paralog (21) | |||||||||
| Structured_description | Concise_description | hum-1 encodes a class I unconventional myosin heavy chain that, within this class, is most closely related to the amoeboid myosin I subclass; loss of hum-1 activity via RNAi results in a low frequency of aldicarb resistance, suggesting that hum-1 may play a role in regulating synapse structure and/or function; when expressed in the DA cholinergic motor neurons, a HUM-1 reporter fusion protein localizes solely to punctate structures. | Paper_evidence | WBPaper00002905 | |||||
| WBPaper00026667 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 15 Jun 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in several cellular components, including actin cytoskeleton; microvillus; and vesicle. Predicted to be part of myosin complex. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 6. Is an ortholog of human MYO1E (myosin IE). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111131 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7599) | ||||
| Molecular_info | Corresponding_CDS | F29D10.4 | |||||||
| Corresponding_transcript | F29D10.4.1 | ||||||||
| Other_sequence (36) | |||||||||
| Associated_feature | WBsf655293 | ||||||||
| WBsf976874 | |||||||||
| WBsf219995 | |||||||||
| WBsf219996 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Chronogram229 | ||||||||
| Expr3572 | |||||||||
| Expr5914 | |||||||||
| Expr1015485 | |||||||||
| Expr1031190 | |||||||||
| Expr1149826 | |||||||||
| Expr2012644 | |||||||||
| Expr2030880 | |||||||||
| Drives_construct | WBCnstr00003792 | ||||||||
| WBCnstr00036505 | |||||||||
| Construct_product | WBCnstr00011496 | ||||||||
| WBCnstr00036505 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (127) | |||||||||
| Interaction (83) | |||||||||
| Map_info | Map | I | Position | 3.22934 | Error | 0.009405 | |||
| Positive | Positive_clone | F29D10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| T08D1 | Author_evidence | Baker JP | |||||||
| Mapping_data | Multi_point | 4425 | |||||||
| 4671 | |||||||||
| 5011 | |||||||||
| 5566 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002905 | ||||||||
| WBPaper00021651 | |||||||||
| WBPaper00024200 | |||||||||
| WBPaper00025258 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064208 | |||||||||
| WBPaper00064860 | |||||||||
| Remark | data received 11/94 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
