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WormBase Tree Display for Gene: WBGene00001816

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Name Class

WBGene00001816SMapS_parentSequenceY48G8AL
IdentityVersion1
NameCGC_namehaf-6Person_evidenceWBPerson36
Sequence_nameY48G8AL.11
Molecular_nameY48G8AL.11a
Y48G8AL.11a.1
CE39850
Y48G8AL.11b
CE49415
Y48G8AL.11c
CE49154
Y48G8AL.11b.1
Y48G8AL.11c.1
Other_nameCELE_Y48G8AL.11Accession_evidenceNDBBX284601
Public_namehaf-6
DB_infoDatabaseAceViewgene1B636
WormQTLgeneWBGene00001816
WormFluxgeneWBGene00001816
NDBlocus_tagCELE_Y48G8AL.11
PanthergeneCAEEL|WormBase=WBGene00001816|UniProtKB=Q9BL17
familyPTHR24221
NCBIgene171694
RefSeqproteinNM_001306301.3
NM_001306302.3
NM_058427.7
TrEMBLUniProtAccV6CLQ7
Q9BL17
V6CKC7
UniProt_GCRPUniProtAccQ9BL17
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhaf
Allele (488)
StrainWBStrain00033045
WBStrain00055353
WBStrain00055356
In_clusterconserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (49)
Paralog (23)
Structured_descriptionConcise_descriptionhaf-6 encodes a half-molecule ATP-binding cassette (ABC) transporter; haf-6 activity is required for efficient RNA interference (RNAi) of genes expressed in the germline and intestine; antibody staining reveals that HAF-6 is expressed in germline and intestinal tissues; in the intestine, HAF-6 colocalizes with an endoplasmic reticulum (ER) protein and in the germline, HAF-6 localization additionally extends to perinuclear regions, an observation also consistent with ER localization.Paper_evidenceWBPaper00027644
Curator_confirmedWBPerson1843
Date_last_updated09 Mar 2007 00:00:00
Automated_descriptionPredicted to enable ATPase-coupled transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in perinuclear endoplasmic reticulum. Expressed in germ line; intestine; and muscle cell. Is an ortholog of human ABCB8 (ATP binding cassette subfamily B member 8).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY48G8AL.11a
Y48G8AL.11b
Y48G8AL.11c
Corresponding_CDS_historyY48G8AL.11:wp154
Corresponding_transcriptY48G8AL.11a.1
Y48G8AL.11b.1
Y48G8AL.11c.1
Other_sequence (32)
Associated_featureWBsf648932
WBsf663908
WBsf663909
WBsf663910
WBsf218960
Experimental_infoRNAi_resultWBRNAi00056962Inferred_automaticallyRNAi_primary
WBRNAi00116497Inferred_automaticallyRNAi_primary
Expr_patternExpr3351
Expr3352
Expr4794
Expr4795
Expr1020032
Expr1031065
Expr1160411
Expr2012359
Expr2030595
Drives_constructWBCnstr00011348
WBCnstr00011349
WBCnstr00012250
Construct_productWBCnstr00012250
AntibodyWBAntibody00001096
Microarray_results (16)
Expression_cluster (191)
Interaction (23)
Map_infoMapIPosition-16.922Error0.003346
PositivePositive_cloneY48G8ALInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkSequence connection from Sheps JA and Baillie DL [021008 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene