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WormBase Tree Display for Gene: WBGene00001708

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Name Class

WBGene00001708EvidencePerson_evidenceWBPerson242
SMapS_parentSequenceF19C6
IdentityVersion1
NameCGC_namegrk-1Person_evidenceWBPerson242
Sequence_nameF19C6.1
Molecular_nameF19C6.1
F19C6.1.1
CE01554
Other_nameCELE_F19C6.1Accession_evidenceNDBBX284606
Public_namegrk-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgrk
Allele (165)
StrainWBStrain00001863
WBStrain00030532
WBStrain00031895
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (52)
ParalogWBGene00001709Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017950Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptiongrk-1 encodes a serine/threonine protein kinase that is most closely related to G protein-coupled receptor (GPCR) kinases.Paper_evidenceWBPaper00013467
Curator_confirmedWBPerson1843
Date_last_updated20 Jul 2007 00:00:00
Automated_descriptionPredicted to enable protein kinase activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Oguchi disease-2; essential hypertension; and rheumatoid arthritis. Is an ortholog of human GRK5 (G protein-coupled receptor kinase 5) and GRK6 (G protein-coupled receptor kinase 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:7148Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4544,HGNC:4545)
DOID:2559Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4545)
DOID:6000Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4544)
DOID:0110713Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10013)
DOID:14330Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4544,HGNC:4545)
DOID:10825Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4543)
DOID:8499Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10013)
Molecular_infoCorresponding_CDSF19C6.1
Corresponding_transcriptF19C6.1.1
Other_sequence (44)
Associated_feature (15)
Experimental_infoRNAi_resultWBRNAi00045000Inferred_automaticallyRNAi_primary
WBRNAi00031123Inferred_automaticallyRNAi_primary
WBRNAi00013547Inferred_automaticallyRNAi_primary
Expr_patternChronogram1419
Expr5794
Expr5795
Expr1014775
Expr1031021
Expr1148967
Expr2012242
Expr2030478
Drives_constructWBCnstr00002656
WBCnstr00004386
WBCnstr00036752
Construct_productWBCnstr00036752
Microarray_results (24)
Expression_cluster (124)
Interaction (44)
Map_infoMapXPosition1.73256Error0.000253
PositivePositive_cloneF19C6Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4879
4314
5083
5561
Reference (15)
Remarkno mutant available yet for this gene [Hart A][030331 ck1]
MethodGene