WormBase Tree Display for Gene: WBGene00001697
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| WBGene00001697 | Evidence | Paper_evidence | WBPaper00003717 | |||
|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C37C3 | |||
| Identity (6) | ||||||
| Gene_info | Biotype | SO:0001217 | ||||
| Gene_class | grd | |||||
| Allele (22) | ||||||
| RNASeq_FPKM (74) | ||||||
| GO_annotation | 00076712 | |||||
| Ortholog (19) | ||||||
| Paralog (26) | ||||||
| Structured_description | Concise_description | grd-8 encodes a hedgehog-like protein, with an N-terminal signalsequence, a central low-complexity proline-rich domain, and a C-terminalGround domain; GRD-8 is expressed in larval intestine and neurons; thegrd-8 gene is directly bound by DAF-12 and requires DAF-12 for fulltranscription; GRD-8's Ground domain is predicted to form acysteine-crosslinked protein involved in intercellular signalling, andit has subtle similarity to the N-terminal Hedge domain of HEDGEHOGproteins; GRD-8 is weakly required for normal molting; GRD-8 is alsorequired for normal adult alae formation, growth to full size,locomotion, and male tail development; all of these requirements mayreflect common defects in cholesterol-dependent hedgehog-like signallingor in vesicle trafficking. | Paper_evidence | WBPaper00003717 | ||
| WBPaper00006525 | ||||||
| WBPaper00024491 | ||||||
| WBPaper00026841 | ||||||
| WBPaper00027263 | ||||||
| Curator_confirmed | WBPerson48 | |||||
| WBPerson567 | ||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | |||||
| Automated_description | Acts upstream of or within nematode male tail mating organ morphogenesis. Expressed in OLLL and OLLR. | Paper_evidence | WBPaper00065943 | |||
| Curator_confirmed | WBPerson324 | |||||
| WBPerson37462 | ||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
| Date_last_updated | 29 Nov 2023 00:00:00 | |||||
| Molecular_info | Corresponding_CDS | C37C3.4 | ||||
| Corresponding_CDS_history | C37C3.4:wp101 | |||||
| Corresponding_transcript | C37C3.4.1 | |||||
| Experimental_info | RNAi_result | WBRNAi00077021 | Inferred_automatically | RNAi_primary | ||
| WBRNAi00011716 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00076997 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00042108 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00076974 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00029637 | Inferred_automatically | RNAi_primary | ||||
| Expr_pattern | Expr639 | |||||
| Expr4434 | ||||||
| Expr5458 | ||||||
| Expr1010876 | ||||||
| Expr1031013 | ||||||
| Expr1146109 | ||||||
| Expr2012238 | ||||||
| Expr2030474 | ||||||
| Drives_construct | WBCnstr00003877 | |||||
| WBCnstr00011997 | ||||||
| WBCnstr00012463 | ||||||
| WBCnstr00036759 | ||||||
| Construct_product | WBCnstr00036759 | |||||
| Microarray_results (19) | ||||||
| Expression_cluster (22) | ||||||
| Interaction | WBInteraction000005600 | |||||
| WBInteraction000380891 | ||||||
| WBInteraction000396823 | ||||||
| WBProcess | WBbiopr:00000123 | |||||
| Map_info | Map | V | Position | 0.915324 | ||
| Positive | Positive_clone | C37C3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
| Pseudo_map_position | ||||||
| Reference | WBPaper00002823 | |||||
| WBPaper00003717 | ||||||
| WBPaper00026841 | ||||||
| WBPaper00028754 | ||||||
| WBPaper00031588 | ||||||
| WBPaper00064105 | ||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
| Method | Gene |
