WormBase Tree Display for Gene: WBGene00001122
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WBGene00001122 | SMap | S_parent | Sequence | F46F6 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | dyf | |||||
Allele (113) | ||||||
Legacy_information | [Herman RK] Defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3(m175), ME4(mn346) | |||||
[C.elegansII] m175 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3(m175), ME4(mn346) OA1: mn346mut. [Starich et al. 1995] | ||||||
Complementation_data | [Herman RK] dyf-6(m175) complements dyf-7(m537), dyf-12(sa127), daf-12(m20) and vab-3(e648) with respect to dye filling. dyf-6(mn346) complements dyf-12(sa122) and vab-3(e648) with respect to dye filling. | |||||
Strain | WBStrain00034381 | |||||
WBStrain00034417 | ||||||
WBStrain00036858 | ||||||
WBStrain00036887 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (18) | ||||||
Ortholog (40) | ||||||
Structured_description | Concise_description | dyf-6 encodes several proteins that, while novel, contain orthologs in Drosophila and mammals; during development, dyf-6 activity is essential for establishing the normal dendritic length of the amphid and phasmid chemosensory neurons; a DYF-6::GFP reporter is expressed in amphid and phasmid neurons where it: 1) localizes to dendritic bodies and endings as well as to cell bodies, and 2) appears to undergo intraflagellar transport (IFT); DYF-6::GFP is also seen in hypodermal cells and in additional neurons, including inner labial neurons and a lateral neuron in the vicinity of PDE; genetic mosaic analyses indicate that dyf-6 functions autonomously at the level of the amphid dendritic bundle to regulate proper dendritic morphology. | Paper_evidence | WBPaper00002087 | ||
WBPaper00027360 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 23 Feb 2007 00:00:00 | |||||
Automated_description | Involved in intraciliary transport and non-motile cilium assembly. Located in dendrite and neuronal cell body. Expressed in ciliated neurons and hypodermis. Is an ortholog of human IFT46 (intraflagellar transport 46). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | F46F6.4a | ||||
F46F6.4b | ||||||
F46F6.4c | ||||||
F46F6.4d | ||||||
Corresponding_CDS_history | F46F6.4:wp163 | |||||
Corresponding_transcript | F46F6.4a.1 | |||||
F46F6.4b.1 | ||||||
F46F6.4c.1 | ||||||
F46F6.4c.2 | ||||||
F46F6.4d.1 | ||||||
Other_sequence | CR03480 | |||||
CRC02533_1 | ||||||
Oden_isotig25770 | ||||||
JI479891.1 | ||||||
Associated_feature (14) | ||||||
Experimental_info | RNAi_result | WBRNAi00015120 | Inferred_automatically | RNAi_primary | ||
WBRNAi00047566 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00047565 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr4523 | |||||
Expr1017659 | ||||||
Expr1030717 | ||||||
Expr1151403 | ||||||
Expr2011136 | ||||||
Expr2029372 | ||||||
Drives_construct | WBCnstr00012076 | |||||
WBCnstr00016048 | ||||||
WBCnstr00037074 | ||||||
Construct_product | WBCnstr00012076 | |||||
WBCnstr00037074 | ||||||
Microarray_results (33) | ||||||
Expression_cluster (125) | ||||||
Interaction (32) | ||||||
Map_info (3) | ||||||
Reference (15) | ||||||
Method | Gene |