WormBase Tree Display for Gene: WBGene00000964
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WBGene00000964 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C47E12 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | dhp-2 | Person_evidence | WBPerson211 | |||||
Sequence_name | C47E12.8 | ||||||||
Molecular_name | C47E12.8 | ||||||||
C47E12.8.1 | |||||||||
CE05452 | |||||||||
Other_name (2) | |||||||||
Public_name | dhp-2 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | dhp | ||||||||
Allele (39) | |||||||||
Legacy_information | common ancestor of CRMP and dihydropyrimidinase [Takemoto et al via email13] | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (58) | |||||||||
Paralog | WBGene00000963 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00006769 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748). | Paper_evidence | WBPaper00004637 | |||||
Curator_confirmed | WBPerson1823 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in pyrimidine nucleobase catabolic process. Located in cytoplasm. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Is an ortholog of human DPYS (dihydropyrimidinase). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:653 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||||
DOID:0060565 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20637) | ||||||
DOID:0111629 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||||||
Molecular_info | Corresponding_CDS | C47E12.8 | |||||||
Corresponding_transcript | C47E12.8.1 | ||||||||
Other_sequence (50) | |||||||||
Associated_feature | WBsf646270 | ||||||||
WBsf997529 | |||||||||
WBsf997530 | |||||||||
WBsf1018033 | |||||||||
WBsf228909 | |||||||||
Experimental_info | RNAi_result | WBRNAi00042682 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089011 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00012077 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00029914 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr835 | ||||||||
Expr836 | |||||||||
Expr1013617 | |||||||||
Expr1030599 | |||||||||
Expr1146671 | |||||||||
Expr2010891 | |||||||||
Expr2029130 | |||||||||
Drives_construct | WBCnstr00013281 | ||||||||
WBCnstr00037174 | |||||||||
Construct_product | WBCnstr00013281 | ||||||||
WBCnstr00037174 | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (131) | |||||||||
Interaction (12) | |||||||||
Map_info | Map | IV | Position | 4.4581 | Error | 0.000963 | |||
Positive | Positive_clone | C47E12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00004552 | ||||||||
WBPaper00010035 | |||||||||
WBPaper00023701 | |||||||||
WBPaper00033099 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00065140 | |||||||||
WBPaper00065331 | |||||||||
Remark | Sequence connection from [Kimura H] | ||||||||
Synonyms : ULIP-A, CeCRMP/DHP-2 | |||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |