WormBase Tree Display for Gene: WBGene00000964
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WBGene00000964 | Evidence | CGC_data_submission | |||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C47E12 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | dhp | ||||||
Allele (39) | |||||||
Legacy_information | common ancestor of CRMP and dihydropyrimidinase [Takemoto et al via email13] | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (16) | |||||||
Ortholog (58) | |||||||
Paralog | WBGene00000963 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00006769 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748). | Paper_evidence | WBPaper00004637 | |||
Curator_confirmed | WBPerson1823 | ||||||
WBPerson567 | |||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in pyrimidine nucleobase catabolic process. Located in cytoplasm. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Is an ortholog of human DPYS (dihydropyrimidinase). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:653 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||
DOID:0060565 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20637) | ||||
DOID:0111629 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3013) | ||||
Molecular_info | Corresponding_CDS | C47E12.8 | |||||
Corresponding_transcript | C47E12.8.1 | ||||||
Other_sequence (50) | |||||||
Associated_feature | WBsf646270 | ||||||
WBsf997529 | |||||||
WBsf997530 | |||||||
WBsf1018033 | |||||||
WBsf228909 | |||||||
Experimental_info (7) | |||||||
Map_info | Map | IV | Position | 4.4581 | Error | 0.000963 | |
Positive | Positive_clone | C47E12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00004552 | ||||||
WBPaper00010035 | |||||||
WBPaper00023701 | |||||||
WBPaper00033099 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00065140 | |||||||
WBPaper00065331 | |||||||
Remark | Sequence connection from [Kimura H] | ||||||
Synonyms : ULIP-A, CeCRMP/DHP-2 | |||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |