WormBase Tree Display for Gene: WBGene00000879
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WBGene00000879 | SMap | S_parent | Sequence | Y75B12B | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cyn-3 | Person_evidence | WBPerson466 | |||||
Sequence_name | Y75B12B.5 | ||||||||
Molecular_name | Y75B12B.5 | ||||||||
Y75B12B.5.1 | |||||||||
CE20374 | |||||||||
Other_name | cyp-3 | Person_evidence | WBPerson466 | ||||||
CELE_Y75B12B.5 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | cyn-3 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 20 Sep 2004 16:20:03 | WBPerson1971 | Name_change | CGC_name | cyp-3 -> cyn-3 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cyn | ||||||||
Allele (28) | |||||||||
Legacy_information | [C.elegansII] NMK. Cyclophilin family, transspliced to SL1. YAC Y15F7. [TP] | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Contained_in_operon | CEOP5521 | ||||||||
Ortholog (54) | |||||||||
Paralog (18) | |||||||||
Structured_description | Concise_description | cyn-3 encodes an abundantly expressed cyclophilin A isoform with peptidyl-prolyl isomerase activity in vitro, which closely resembles the prototypical CypA and is thus likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; cyn-3 is exclusively expressed in the single anterior excretory cell, and is dispensable for viability and gross morphology in mass RNAi screens. | Paper_evidence | WBPaper00002472 | |||||
WBPaper00003820 | |||||||||
WBPaper00005654 | |||||||||
WBPaper00026884 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 20 Mar 2007 00:00:00 | ||||||||
Automated_description | Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in obsolete cell. Expressed in excretory system. Human ortholog(s) of this gene implicated in several diseases, including Bell's palsy; aggressive periodontitis; and gastrointestinal system cancer (multiple). Is an ortholog of human PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (5) | ||||||||
Molecular_info | Corresponding_CDS | Y75B12B.5 | |||||||
Corresponding_transcript | Y75B12B.5.1 | ||||||||
Other_sequence (202) | |||||||||
Associated_feature | WBsf647585 | ||||||||
WBsf977375 | |||||||||
WBsf977376 | |||||||||
WBsf1002255 | |||||||||
WBsf1002256 | |||||||||
WBsf1020992 | |||||||||
WBsf233011 | |||||||||
Experimental_info (7) | |||||||||
Map_info | Map | V | Position | 7.54862 | Error | 0.006411 | |||
Positive | Positive_clone | Y15F7 | Author_evidence | Page AM | |||||
Y75B12B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
ZK526 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00002472 | ||||||||
WBPaper00003820 | |||||||||
WBPaper00018604 | |||||||||
WBPaper00026884 | |||||||||
WBPaper00032230 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00041771 | |||||||||
WBPaper00049828 | |||||||||
WBPaper00055090 | |||||||||
Remark | [Page AM] Is transpliced by SL-1. Isolated from mixed stage cDNA by A. P. Page using SL1, and known 3' seq from CEESH95F. (not mapped); Genbank U31077. | ||||||||
[JAH]Partial sequence identity 64% to human CYP gene, 66% to yeast CSBY. | |||||||||
CEESH95F,CEMSB85F,CEMSB85FB,CEMSB85R removed from sequence list and replaced by genomic_canonical Y75B12B.5. sdm 11/00 | |||||||||
PPIase or cyclophilin, EC 5.2.1.8 | |||||||||
This gene has been renamed with approval of the CGC (cyp-3->cyn-3) | Person_evidence | WBPerson466 | |||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |