WormBase Tree Display for Gene: WBGene00000869
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| WBGene00000869 | Evidence | Paper_evidence | WBPaper00005624 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C54G4 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | cyc-1 | |||||||
| Sequence_name | C54G4.8 | ||||||||
| Molecular_name | C54G4.8 | ||||||||
| C54G4.8.1 | |||||||||
| CE05514 | |||||||||
| Other_name | CELE_C54G4.8 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | cyc-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyc | ||||||||
| Allele (26) | |||||||||
| Strain | WBStrain00031929 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP1448 | ||||||||
| Ortholog (40) | |||||||||
| Structured_description | Concise_description | cyc-1 encodes a component of complex III ( cytochrome c reductase) required for normal ATP production; reduction of ATP production by cyc-1(RNAi) decreases growth rate and body size, slows behavior, and increases lifespan; cyc-1 encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial | Paper_evidence | WBPaper00004424 | |||||
| WBPaper00005624 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 09 Aug 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable electron transfer activity; heme binding activity; and metal ion binding activity. Involved in determination of adult lifespan and proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex III. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Is an ortholog of human CYC1 (cytochrome c1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080115 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2579) | ||||
| Molecular_info | Corresponding_CDS | C54G4.8 | |||||||
| Corresponding_transcript | C54G4.8.1 | ||||||||
| Other_sequence (90) | |||||||||
| Associated_feature | WBsf664507 | ||||||||
| WBsf219856 | |||||||||
| WBsf219857 | |||||||||
| WBsf219858 | |||||||||
| WBsf219859 | |||||||||
| WBsf219860 | |||||||||
| Experimental_info | RNAi_result (38) | ||||||||
| Expr_pattern | Expr4064 | ||||||||
| Expr1022424 | |||||||||
| Expr1030536 | |||||||||
| Expr1147161 | |||||||||
| Expr2010650 | |||||||||
| Expr2028890 | |||||||||
| Drives_construct | WBCnstr00037235 | ||||||||
| Construct_product | WBCnstr00037235 | ||||||||
| Regulate_expr_cluster | WBPaper00033065:cyc-1(RNAi)_downregulated | ||||||||
| WBPaper00033065:cyc-1(RNAi)_upregulated | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (106) | |||||||||
| Interaction (196) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | I | Position | 2.42266 | Error | 0.001101 | |||
| Positive | Positive_clone | C54G4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4893 | |||||||
| 4159 | |||||||||
| 4539 | |||||||||
| 5616 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (24) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
