WormBase Tree Display for Gene: WBGene00000556
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| WBGene00000556 | Evidence | Person_evidence | WBPerson168 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | R09B5 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | cnc-2 | Person_evidence | WBPerson168 | |||||
| Sequence_name | R09B5.3 | ||||||||
| Molecular_name | R09B5.3a | ||||||||
| R09B5.3a.1 | |||||||||
| CE12622 | |||||||||
| R09B5.3b | |||||||||
| CE50928 | |||||||||
| R09B5.3a.2 | |||||||||
| R09B5.3b.1 | |||||||||
| Other_name | CELE_R09B5.3 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | cnc-2 | ||||||||
| DB_info | Database | AceView | gene | 5B928 | |||||
| WormQTL | gene | WBGene00000556 | |||||||
| WormFlux | gene | WBGene00000556 | |||||||
| NDB | locus_tag | CELE_R09B5.3 | |||||||
| NCBI | gene | 178637 | |||||||
| RefSeq | protein | NM_001313243.2 | |||||||
| NM_071017.6 | |||||||||
| TrEMBL | UniProtAcc | O44611 | |||||||
| A0A0K3ASA3 | |||||||||
| UniProt_GCRP | UniProtAcc | O44611 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cnc | ||||||||
| Allele (31) | |||||||||
| Strain | WBStrain00033049 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00000947 | ||||||||
| 00032942 | |||||||||
| 00032943 | |||||||||
| 00032944 | |||||||||
| 00032945 | |||||||||
| 00032946 | |||||||||
| 00105990 | |||||||||
| 00105997 | |||||||||
| Ortholog | WBGene00028822 | Caenorhabditis briggsae | Person_evidence | WBPerson2531 | |||||
| WBPerson168 | |||||||||
| WBGene00045439 | Caenorhabditis remanei | From_analysis | OMA | ||||||
| WBGene00156857 | Caenorhabditis brenneri | From_analysis | OMA | ||||||
| chrV_pilon.g13223 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | cnc-2 encodes one of eleven C. elegans caenacin peptides; cnc-2 functions as a secreted antimicrobial peptide in the innate immune response: cnc-2 expression is strongly induced in the epidermis upon infection by the fungal pathogen and overexpression of cnc-2 promotes survival after D. coniospora infection; cnc-2 expression is also induced upon infection by the Gram negative bacterium Serratia marcescens; cnc-2 expression is positively regulated by the DBL-1 TGF-beta homolog, the SMA-6/DAF-4 TGF-beta receptor, and the SMA-3, but not SMA-2 and SMA-4, SMAD protein. | Paper_evidence | WBPaper00005382 | |||||
| WBPaper00006488 | |||||||||
| WBPaper00032891 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 04 Jan 2010 00:00:00 | ||||||||
| Automated_description | Involved in defense response to Gram-negative bacterium; defense response to fungus; and innate immune response. Predicted to be located in extracellular space. Expressed in hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R09B5.3a | |||||||
| R09B5.3b | |||||||||
| Corresponding_transcript | R09B5.3a.1 | ||||||||
| R09B5.3a.2 | |||||||||
| R09B5.3b.1 | |||||||||
| Other_sequence (11) | |||||||||
| Associated_feature | WBsf652472 | ||||||||
| WBsf233334 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00082482 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00034770 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017629 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098169 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051597 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112259 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00075969 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001386 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8217 | ||||||||
| Expr8525 | |||||||||
| Expr1012281 | |||||||||
| Expr1155271 | |||||||||
| Expr2010263 | |||||||||
| Expr2028505 | |||||||||
| Drives_construct (14) | |||||||||
| Construct_product | WBCnstr00037455 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (235) | |||||||||
| Interaction (16) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| Map_info | Map | V | Position | -18.9161 | Error | 0.001788 | |||
| Positive | Positive_clone | R09B5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
