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WormBase Tree Display for Gene: WBGene00000543

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Name Class

WBGene00000543SMapS_parentSequenceT04A8
IdentityVersion1
NameCGC_nameclp-2Person_evidenceWBPerson349
Sequence_nameT04A8.16
Molecular_nameT04A8.16
T04A8.16.1
CE01070
Other_nameCELE_T04A8.16Accession_evidenceNDBBX284603
Public_nameclp-2
DB_infoDatabaseAceViewgene3F790
WormQTLgeneWBGene00000543
WormFluxgeneWBGene00000543
NDBlocus_tagCELE_T04A8.16
PanthergeneCAEEL|WormBase=WBGene00000543|UniProtKB=Q22143
familyPTHR46143
NCBIgene175618
RefSeqproteinNM_065563.5
TREEFAMTREEFAM_IDTF322245
TrEMBLUniProtAccQ22143
UniProt_GCRPUniProtAccQ22143
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classclp
Allele (49)
StrainWBStrain00003127
WBStrain00028932
RNASeq_FPKM (74)
GO_annotation (11)
Contained_in_operonCEOP3835
Ortholog (39)
Paralog (13)
Structured_descriptionConcise_descriptionclp-2 encodes a large calpain subunit that contains two predicted MIT (microtubule interacting and trafficking) domains and is homologous to the mammalian Calpain 7 proteins and the atypical, nuclear-localized Aspergillus calpain, PalB; by homology, CLP-2 is predicted to function as a calcium-dependent, cysteine protease that is involved in intracellular proteolysis and peptidolysis; however, as loss of clp-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of CLP-2 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00004403
WBPaper00005654
WBPaper00005655
WBPaper00013602
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Expressed in head; hypodermis; intestinal cell; muscle cell; and tail. Is an ortholog of human CAPN7 (calpain 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST04A8.16
Corresponding_transcriptT04A8.16.1
Other_sequence (33)
Associated_featureWBsf650994
WBsf226564
Experimental_infoRNAi_result (14)
Expr_patternChronogram1965
Expr10017
Expr14807
Expr14808
Expr1025088
Expr1030325
Expr1155970
Expr2010244
Expr2028486
Drives_constructWBCnstr00003610
WBCnstr00014646
WBCnstr00037462
WBCnstr00041428
Construct_productWBCnstr00014651
WBCnstr00014657
WBCnstr00037462
WBCnstr00041428
Microarray_results (19)
Expression_cluster (94)
InteractionWBInteraction000211228
WBInteraction000288834
WBInteraction000354160
WBInteraction000439806
WBInteraction000548620
Map_infoMapIIIPosition-2.81896Error0.002299
PositivePositive_cloneT04A8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005513
WBPaper00027531
WBPaper00038491
WBPaper00055090
WBPaper00061251
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene