WormBase Tree Display for Gene: WBGene00000419
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WBGene00000419 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | ced-5 | Person_evidence | WBPerson261 | |||||
Sequence_name | C02F4.1 | ||||||||
Molecular_name | C02F4.1 | ||||||||
C02F4.1.1 | |||||||||
CE24779 | |||||||||
Other_name | CELE_C02F4.1 | Accession_evidence | NDB | BX284604 | |||||
Public_name | ced-5 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ced | ||||||||
Allele (106) | |||||||||
Legacy_information (3) | |||||||||
Strain | WBStrain00027132 | ||||||||
WBStrain00027134 | |||||||||
WBStrain00027167 | |||||||||
WBStrain00027174 | |||||||||
WBStrain00027281 | |||||||||
WBStrain00027282 | |||||||||
WBStrain00027293 | |||||||||
WBStrain00027342 | |||||||||
WBStrain00031450 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (48) | |||||||||
Ortholog (59) | |||||||||
Paralog | WBGene00009065 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
WBGene00018520 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | ced-5 encodes a homolog of the human protein DOCK180; ced-5 is required for the cell engulfment stage of programmed cell death, and physically interacts with CED-2. | Paper_evidence | WBPaper00003036 | |||||
WBPaper00003948 | |||||||||
WBPaper00005004 | |||||||||
WBPaper00012851 | |||||||||
WBPaper00013593 | |||||||||
WBPaper00013632 | |||||||||
WBPaper00038460 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 29 Jun 2012 00:00:00 | ||||||||
Automated_description | Enables SH3 domain binding activity and enzyme binding activity. Involved in several processes, including left/right axis specification; positive regulation of distal tip cell migration; and vesicle-mediated transport. Located in presynapse. Part of guanyl-nucleotide exchange factor complex. Expressed in body wall muscle cell; hermaphrodite somatic gonadal cell; and intestinal cell. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and immunodeficiency 40. Is an ortholog of human DOCK2 (dedicator of cytokinesis 2) and DOCK5 (dedicator of cytokinesis 5). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0111951 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2988) | ||||
DOID:1094 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2989) | ||||||
Molecular_info | Corresponding_CDS | C02F4.1 | |||||||
Corresponding_transcript | C02F4.1.1 | ||||||||
Other_sequence (13) | |||||||||
Associated_feature | WBsf646307 | ||||||||
WBsf660584 | |||||||||
WBsf976954 | |||||||||
WBsf976955 | |||||||||
WBsf976956 | |||||||||
WBsf228996 | |||||||||
WBsf228997 | |||||||||
WBsf228998 | |||||||||
Experimental_info | RNAi_result (11) | ||||||||
Expr_pattern | Expr8762 | ||||||||
Expr14253 | |||||||||
Expr1020545 | |||||||||
Expr1030235 | |||||||||
Expr1143552 | |||||||||
Expr2009849 | |||||||||
Expr2028089 | |||||||||
Drives_construct | WBCnstr00005770 | ||||||||
WBCnstr00037557 | |||||||||
WBCnstr00040684 | |||||||||
Construct_product | WBCnstr00014899 | ||||||||
WBCnstr00037557 | |||||||||
Microarray_results (24) | |||||||||
Expression_cluster (132) | |||||||||
Interaction (129) | |||||||||
WBProcess (5) | |||||||||
Map_info | Map | IV | Position | 4.61067 | Error | 0.002681 | |||
Well_ordered | |||||||||
Positive | Positive_clone | C02F4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
ZK188 | |||||||||
Mapping_data | Multi_point | 1517 | |||||||
1518 | |||||||||
1520 | |||||||||
1521 | |||||||||
1522 | |||||||||
1523 | |||||||||
1820 | |||||||||
1822 | |||||||||
4720 | |||||||||
Pos_neg_data | 4243 | ||||||||
Reference (191) | |||||||||
Method | Gene |