WormBase Tree Display for Gene: WBGene00000413
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| WBGene00000413 | SMap | S_parent | Sequence | Y54E10A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cdt-1 | Person_evidence | WBPerson322 | |||||
| Sequence_name | Y54E10A.15 | ||||||||
| Molecular_name | Y54E10A.15 | ||||||||
| Y54E10A.15.1 | |||||||||
| CE22447 | |||||||||
| Other_name | CELE_Y54E10A.15 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | cdt-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00000413 | |||||
| WormFlux | gene | WBGene00000413 | |||||||
| NDB | locus_tag | CELE_Y54E10A.15 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000413|UniProtKB=Q86S68 | |||||||
| family | PTHR28637 | ||||||||
| NCBI | gene | 171896 | |||||||
| RefSeq | protein | NM_001047242.4 | |||||||
| TREEFAM | TREEFAM_ID | TF101159 | |||||||
| TrEMBL | UniProtAcc | Q86S68 | |||||||
| UniProt_GCRP | UniProtAcc | Q86S68 | |||||||
| OMIM | gene | 605525 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cdt | ||||||||
| Allele (93) | |||||||||
| Strain | WBStrain00051136 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Contained_in_operon | CEOP1944 | ||||||||
| Ortholog (30) | |||||||||
| Structured_description | Concise_description | cdt-1 encodes the C. elegans ortholog of the replication-licensing factor Cdt1; CDT-1 activity is essential for DNA replication; CDT-1 levels are negatively regulated by a CUL-4-containing ubiquitin ligase complex. | Paper_evidence | WBPaper00005912 | |||||
| WBPaper00028868 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 03 Dec 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA binding activity and DNA polymerase binding activity. Involved in positive regulation of nematode male tail tip morphogenesis. Located in cytoplasm and nucleus. Part of chromatin. Expressed in anchor cell; germ line; uterine epithelial cell; and vulD. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Is an ortholog of human CDT1 (chromatin licensing and DNA replication factor 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080515 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:24576) | ||||
| Molecular_info | Corresponding_CDS | Y54E10A.15 | |||||||
| Corresponding_CDS_history | Y54E10A.15a:wp154 | ||||||||
| Y54E10A.15b:wp102 | |||||||||
| Y54E10A.15b:wp154 | |||||||||
| Corresponding_transcript | Y54E10A.15.1 | ||||||||
| Other_sequence | CJC07546_1 | ||||||||
| CR06574 | |||||||||
| CRC10573_1 | |||||||||
| CBC14493_1 | |||||||||
| CRC01944_1 | |||||||||
| CBC05093_1 | |||||||||
| JI468640.1 | |||||||||
| CR00767 | |||||||||
| CBC05545_1 | |||||||||
| Associated_feature | WBsf649013 | ||||||||
| WBsf976651 | |||||||||
| WBsf976652 | |||||||||
| WBsf983088 | |||||||||
| WBsf219111 | |||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00000442 | ||||||||
| WBCnstr00042819 | |||||||||
| Construct_product | WBCnstr00000442 | ||||||||
| WBCnstr00019393 | |||||||||
| WBCnstr00042819 | |||||||||
| Antibody | WBAntibody00000626 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (161) | |||||||||
| Interaction (95) | |||||||||
| Map_info | Map | I | Position | -4.45779 | Error | 0.003381 | |||
| Positive | Positive_clone | Y54E10A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
