WormBase Tree Display for Gene: WBGene00000408
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| WBGene00000408 | Evidence | Accession_evidence | EMBL | AF154004 | |||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | Y39G10AL | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | cdk-7 | Person_evidence | WBPerson346 | |||||
| Sequence_name | Y39G10AL.3 | ||||||||
| Molecular_name | Y39G10AL.3 | ||||||||
| Y39G10AL.3.1 | |||||||||
| CE30320 | |||||||||
| Y39G10AL.3.2 | |||||||||
| Y39G10AL.3.3 | |||||||||
| Other_name | CELE_Y39G10AL.3 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | cdk-7 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cdk | ||||||||
| Allele (221) | |||||||||
| Strain | WBStrain00022247 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (34) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | The cdk-7 gene encodes a cyclin-dependent kinase orthologous to human CDK7 (OMIM:601955) that is a component of the general transcription factor IIH (TFIIH) complex; CDK-7 is required during embryogenesis for mRNA transcription and phosphorylation of RNA polymerase II on serine 2 and serine 5, as well as for cell cycle progression, maintenance of ploidy, and completion of meiosis following fertilization. | Paper_evidence | WBPaper00005224 | |||||
| WBPaper00005411 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Involved in mRNA transcription and mitotic cell cycle, embryonic. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription factor TFIIK complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human CDK7 (cyclin dependent kinase 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1778) | ||||
| Molecular_info | Corresponding_CDS | Y39G10AL.3 | |||||||
| Corresponding_transcript | Y39G10AL.3.1 | ||||||||
| Y39G10AL.3.2 | |||||||||
| Y39G10AL.3.3 | |||||||||
| Other_sequence | EX558809.1 | ||||||||
| Tcir_isotig08602 | |||||||||
| EX567269.1 | |||||||||
| EX553152.1 | |||||||||
| MH03762 | |||||||||
| Associated_feature | WBsf648961 | ||||||||
| WBsf980957 | |||||||||
| WBsf219016 | |||||||||
| WBsf219017 | |||||||||
| Transcription_factor | WBTranscriptionFactor000151 | ||||||||
| WBTranscriptionFactor000683 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00027892 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00024334 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00108295 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087260 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087254 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087257 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024335 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000443 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00056261 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1023789 | ||||||||
| Expr1030225 | |||||||||
| Expr1159744 | |||||||||
| Expr2009813 | |||||||||
| Expr2028054 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (110) | |||||||||
| Interaction (147) | |||||||||
| Map_info | Map | I | Position | -9.87116 | Error | 0.188307 | |||
| Positive | Positive_clone | Y39G10AL | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4198 | |||||||
| 5304 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
