WormBase Tree Display for Gene: WBGene00000270
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| WBGene00000270 | SMap | S_parent | Sequence | T12G3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | bre-5 | Person_evidence | WBPerson26 | |||||
| Sequence_name | T12G3.8 | ||||||||
| Molecular_name | T12G3.8a | ||||||||
| T12G3.8a.1 | |||||||||
| CE30354 | |||||||||
| T12G3.8b | |||||||||
| CE46002 | |||||||||
| T12G3.8b.1 | |||||||||
| Other_name | CELE_T12G3.8 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | bre-5 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | bre | ||||||||
| Allele (25) | |||||||||
| Legacy_information | [Marroquin LD, Aroian RV ] Resistant to Bt toxin, Cry5B | ||||||||
| Strain | WBStrain00008571 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (76) | |||||||||
| Paralog (18) | |||||||||
| Structured_description | Concise_description | The bre-5 gene encodes a putative beta-1,3-galactosyltransferase that is predicted to transfer galactose onto proteins or lipids; BRE-5 is required for Cry5B toxicity. | Paper_evidence | WBPaper00004264 | |||||
| WBPaper00004776 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables acetylglucosaminyltransferase activity. Involved in several processes, including carbohydrate biosynthetic process; positive regulation of Notch signaling pathway; and regulation of mesodermal cell fate specification. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human B3GALNT1 (beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)); B3GALT9 (beta-1,3-galactosyltransferase 9); and B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:920) | ||||
| Molecular_info | Corresponding_CDS | T12G3.8a | |||||||
| T12G3.8b | |||||||||
| Corresponding_transcript | T12G3.8a.1 | ||||||||
| T12G3.8b.1 | |||||||||
| Other_sequence | AY038065 | ||||||||
| CBC03826_1 | |||||||||
| Acan_isotig13026 | |||||||||
| CBC02772_1 | |||||||||
| CJC01483_1 | |||||||||
| Associated_feature | WBsf652271 | ||||||||
| WBsf230953 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00063080 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00053227 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1019825 | ||||||||
| Expr1156816 | |||||||||
| Expr2009655 | |||||||||
| Expr2027894 | |||||||||
| Drives_construct | WBCnstr00037615 | ||||||||
| Construct_product | WBCnstr00037615 | ||||||||
| Antibody | WBAntibody00001845 | ||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (87) | |||||||||
| Interaction | WBInteraction000004545 | ||||||||
| Anatomy_function | WBbtf0055 | ||||||||
| WBProcess | WBbiopr:00000008 | ||||||||
| Map_info | Map | IV | Position | 5.53829 | Error | 0.01089 | |||
| Positive | Positive_clone | T12G3 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 3919 | |||||||
| 5280 | |||||||||
| Reference (28) | |||||||||
| Remark | Data extracted from Marroquin et al. (2000) | ||||||||
| Cloned, positive rescue by T12G3; unpredicted gene [Griffits JS, Aroian R. krb 14/11/01 | |||||||||
| Sequence connection from kj2 | |||||||||
| Method | Gene |
