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WormBase Tree Display for Gene: WBGene00000269

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Name Class

WBGene00000269EvidencePaper_evidenceWBPaper00006229
SMapS_parentSequenceY73E7A
IdentityVersion1
NameCGC_namebre-4Person_evidenceWBPerson26
Sequence_nameY73E7A.7
Molecular_nameY73E7A.7a
Y73E7A.7a.1
CE26412
Y73E7A.7b
CE49566
Y73E7A.7a.2
Y73E7A.7b.1
Other_nameCELE_Y73E7A.7Accession_evidenceNDBBX284601
Public_namebre-4
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classbre
Allele (256)
Legacy_information[Marroquin LD, Aroian RV ] Resistant to Bt toxin, Cry5B
StrainWBStrain00033007
WBStrain00008568
RNASeq_FPKM (74)
GO_annotation (21)
Ortholog (56)
ParalogWBGene00005021Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00012206Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionbre-4 encodes a beta-1,4-N-acetylgalactosaminyltransferase that is required for the toxicity of Bacillus thuringiensis Cry5B.Paper_evidenceWBPaper00004264
WBPaper00016853
WBPaper00005471
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated29 Nov 2011 00:00:00
Automated_descriptionEnables beta-1,4-N-acetylgalactosaminyltransferase activity. Involved in positive regulation of Notch signaling pathway; protein glycosylation; and response to toxic substance. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IId and multiple sclerosis. Is an ortholog of human B4GALT1 (beta-1,4-galactosyltransferase 1) and B4GALT3 (beta-1,4-galactosyltransferase 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:924)
DOID:2377Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:928)
DOID:5212Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:924)
Molecular_infoCorresponding_CDSY73E7A.7a
Y73E7A.7b
Corresponding_transcriptY73E7A.7a.1
Y73E7A.7a.2
Y73E7A.7b.1
Other_sequence (80)
Experimental_infoRNAi_resultWBRNAi00058368Inferred_automaticallyRNAi_primary
Expr_patternExpr1023430
Expr1030174
Expr1161788
Expr2009654
Expr2027893
Microarray_results (16)
Expression_cluster (66)
InteractionWBInteraction000136535
WBInteraction000136538
WBInteraction000169483
WBInteraction000169747
WBProcessWBbiopr:00000008
Map_infoMapIPosition-13.6349Error0.056752
PositivePositive_cloneY73E7AInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point7119
Multi_point3918
5373
Reference (17)
RemarkData extracted from Marroquin et al. (2000)
MethodGene