WormBase Tree Display for Gene: WBGene00000225
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WBGene00000225 | Evidence | Author_evidence | Veljkovic E | ||||||
---|---|---|---|---|---|---|---|---|---|
Verrey F | |||||||||
SMap | S_parent | Sequence | C38C6 | ||||||
Identity | Version | 2 | |||||||
Name | CGC_name | atgp-2 | |||||||
Sequence_name | C38C6.2 | ||||||||
Molecular_name | C38C6.2a | ||||||||
C38C6.2a.1 | |||||||||
CE31162 | |||||||||
C38C6.2b | |||||||||
CE46309 | |||||||||
C38C6.2c | |||||||||
CE46420 | |||||||||
C38C6.2b.1 | |||||||||
C38C6.2c.1 | |||||||||
Other_name | atg-2 | ||||||||
CELE_C38C6.2 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | atgp-2 | ||||||||
DB_info | Database | AceView | gene | 2O926 | |||||
WormQTL | gene | WBGene00000225 | |||||||
WormFlux | gene | WBGene00000225 | |||||||
NDB | locus_tag | CELE_C38C6.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000225|UniProtKB=O45298 | |||||||
family | PTHR10357 | ||||||||
NCBI | gene | 175125 | |||||||
RefSeq | protein | NM_001267508.3 | |||||||
NM_001267506.4 | |||||||||
NM_001267507.3 | |||||||||
TrEMBL | UniProtAcc | O45298 | |||||||
G1K108 | |||||||||
G1K110 | |||||||||
UniProt_GCRP | UniProtAcc | O45298 | |||||||
OMIM | gene | 104614 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 28 Feb 2008 11:17:12 | WBPerson2970 | Name_change | CGC_name | atgp-2 | ||||
Other_name | atg-2 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | atgp | ||||||||
Allele (86) | |||||||||
Strain | WBStrain00031480 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00008914 | ||||||||
00008915 | |||||||||
00034174 | |||||||||
00034175 | |||||||||
00034176 | |||||||||
00034177 | |||||||||
00034178 | |||||||||
00034179 | |||||||||
00107058 | |||||||||
Ortholog (52) | |||||||||
Paralog | WBGene00000224 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00008220 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00011409 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | atgp-2 encodes an amino acid transporter glycoprotein subunit; when co-expressed in Xenopus oocytes with either the AAT-1 or AAT-3 catalytic subunit, ATGP-2 facilitates amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; when co-expressed with AAT-9, ATGP-2 is able to enhance the activity of this catalytic subunit; ATGP-2 can covalently associate with AAT-1 or AAT-3 in the Xenopus expression system; when co-expressed with AAT-1 or AAT-3, ATGP-2 localizes to the cell surface of oocytes, but when expressed alone, ATGP-2 localizes intracellularly. | Paper_evidence | WBPaper00006408 | |||||
WBPaper00024381 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 03 Mar 2006 00:00:00 | ||||||||
Automated_description | Contributes to L-amino acid transmembrane transporter activity. Involved in amino acid transmembrane transport. Located in plasma membrane. Part of amino acid transport complex. Human ortholog(s) of this gene implicated in cystinuria. Is an ortholog of human SLC3A1 (solute carrier family 3 member 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:9266 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11025) | ||||
Molecular_info | Corresponding_CDS | C38C6.2a | |||||||
C38C6.2b | |||||||||
C38C6.2c | |||||||||
Corresponding_CDS_history | C38C6.2:wp80 | ||||||||
Corresponding_transcript | C38C6.2a.1 | ||||||||
C38C6.2b.1 | |||||||||
C38C6.2c.1 | |||||||||
Other_sequence (56) | |||||||||
Associated_feature | WBsf666390 | ||||||||
WBsf717837 | |||||||||
WBsf990770 | |||||||||
WBsf1013877 | |||||||||
WBsf224300 | |||||||||
Experimental_info | RNAi_result | WBRNAi00029658 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00011749 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00042147 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00103211 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1028562 | ||||||||
Expr1030142 | |||||||||
Expr1146149 | |||||||||
Expr2009499 | |||||||||
Expr2027736 | |||||||||
Antibody | WBAntibody00000720 | ||||||||
Microarray_results (24) | |||||||||
Expression_cluster (134) | |||||||||
Interaction (52) | |||||||||
Map_info | Map | II | Position | 23.2711 | Error | 0.020129 | |||
Positive | Positive_clone | C38C6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4165 | |||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00006408 | ||||||||
WBPaper00024381 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00044410 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00056814 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |