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WormBase Tree Display for Gene: WBGene00000225

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Name Class

WBGene00000225EvidenceAuthor_evidenceVeljkovic E
Verrey F
SMapS_parentSequenceC38C6
IdentityVersion2
NameCGC_nameatgp-2
Sequence_nameC38C6.2
Molecular_nameC38C6.2a
C38C6.2a.1
CE31162
C38C6.2b
CE46309
C38C6.2c
CE46420
C38C6.2b.1
C38C6.2c.1
Other_nameatg-2
CELE_C38C6.2Accession_evidenceNDBBX284602
Public_nameatgp-2
DB_infoDatabaseAceViewgene2O926
WormQTLgeneWBGene00000225
WormFluxgeneWBGene00000225
NDBlocus_tagCELE_C38C6.2
PanthergeneCAEEL|WormBase=WBGene00000225|UniProtKB=O45298
familyPTHR10357
NCBIgene175125
RefSeqproteinNM_001267508.3
NM_001267506.4
NM_001267507.3
TrEMBLUniProtAccO45298
G1K108
G1K110
UniProt_GCRPUniProtAccO45298
OMIMgene104614
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
228 Feb 2008 11:17:12WBPerson2970Name_changeCGC_nameatgp-2
Other_nameatg-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classatgp
Allele (86)
StrainWBStrain00031480
RNASeq_FPKM (74)
GO_annotation00008914
00008915
00034174
00034175
00034176
00034177
00034178
00034179
00107058
Ortholog (52)
ParalogWBGene00000224Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00008220Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00011409Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionatgp-2 encodes an amino acid transporter glycoprotein subunit; when co-expressed in Xenopus oocytes with either the AAT-1 or AAT-3 catalytic subunit, ATGP-2 facilitates amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; when co-expressed with AAT-9, ATGP-2 is able to enhance the activity of this catalytic subunit; ATGP-2 can covalently associate with AAT-1 or AAT-3 in the Xenopus expression system; when co-expressed with AAT-1 or AAT-3, ATGP-2 localizes to the cell surface of oocytes, but when expressed alone, ATGP-2 localizes intracellularly.Paper_evidenceWBPaper00006408
WBPaper00024381
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated03 Mar 2006 00:00:00
Automated_descriptionContributes to L-amino acid transmembrane transporter activity. Involved in amino acid transmembrane transport. Located in plasma membrane. Part of amino acid transport complex. Human ortholog(s) of this gene implicated in cystinuria. Is an ortholog of human SLC3A1 (solute carrier family 3 member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9266Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11025)
Molecular_infoCorresponding_CDSC38C6.2a
C38C6.2b
C38C6.2c
Corresponding_CDS_historyC38C6.2:wp80
Corresponding_transcriptC38C6.2a.1
C38C6.2b.1
C38C6.2c.1
Other_sequence (56)
Associated_featureWBsf666390
WBsf717837
WBsf990770
WBsf1013877
WBsf224300
Experimental_infoRNAi_resultWBRNAi00029658Inferred_automaticallyRNAi_primary
WBRNAi00011749Inferred_automaticallyRNAi_primary
WBRNAi00042147Inferred_automaticallyRNAi_primary
WBRNAi00103211Inferred_automaticallyRNAi_primary
Expr_patternExpr1028562
Expr1030142
Expr1146149
Expr2009499
Expr2027736
AntibodyWBAntibody00000720
Microarray_results (24)
Expression_cluster (134)
Interaction (52)
Map_infoMapIIPosition23.2711Error0.020129
PositivePositive_cloneC38C6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4165
Pseudo_map_position
ReferenceWBPaper00006408
WBPaper00024381
WBPaper00038491
WBPaper00044410
WBPaper00055090
WBPaper00056814
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene