WormBase Tree Display for Gene: WBGene00000188
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| WBGene00000188 | SMap | S_parent | Sequence | F19H8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | arl-3 | |||||||
| Sequence_name | F19H8.3 | ||||||||
| Molecular_name | F19H8.3 | ||||||||
| F19H8.3.1 | |||||||||
| CE15872 | |||||||||
| Other_name | CELE_F19H8.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | arl-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | arl | ||||||||
| Allele (42) | |||||||||
| Legacy_information | ortholog of ARL3 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (47) | |||||||||
| Paralog (14) | |||||||||
| Structured_description | Concise_description | arl-3 encodes a member of the ARL (ADP-ribosylation factor(ARF)-like) family of proteins which are very similar to ARF proteins but lack the ability to stimulate ADP ribosylation by cholera toxin; an arl-3 deletion allele, tm1703, results in essentially wild-type animals that display slight defects in male mating behavior; ARL-3::GFP reporter fusions are expressed in ciliated neurons, where they localize throughout the cell; the arl-3 upstream regulatory region contains an X box sequence, a conserved 14 bp element that may serve as a binding site for DAF-19, an RFX-family transcription factor that controls ciliary gene expression; in yeast two-hybrid studies, ARL-3 interacts with UNC-119, a conserved, novel protein essential for neuronal development. | Paper_evidence | WBPaper00024631 | |||||
| WBPaper00026601 | |||||||||
| WBPaper00027646 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 11 Jun 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTP binding activity. Predicted to be involved in cilium assembly. Predicted to be located in cytoplasm and microtubule cytoskeleton. Expressed in head neurons and tail neurons. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa 83. Is an ortholog of human ARL3 (ADP ribosylation factor like GTPase 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112140 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:694) | ||||
| DOID:0050777 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:694) | ||||||
| Molecular_info | Corresponding_CDS | F19H8.3 | |||||||
| Corresponding_transcript | F19H8.3.1 | ||||||||
| Other_sequence (28) | |||||||||
| Associated_feature | WBsf644865 | ||||||||
| WBsf658425 | |||||||||
| WBsf990762 | |||||||||
| WBsf222489 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00082779 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00082781 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062563 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00082780 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045052 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031145 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00099105 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00103294 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013580 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045049 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3153 | ||||||||
| Expr3736 | |||||||||
| Expr1018446 | |||||||||
| Expr1030111 | |||||||||
| Expr1149011 | |||||||||
| Expr2009401 | |||||||||
| Expr2027637 | |||||||||
| Drives_construct | WBCnstr00008469 | ||||||||
| WBCnstr00008470 | |||||||||
| WBCnstr00008474 | |||||||||
| WBCnstr00008475 | |||||||||
| WBCnstr00011181 | |||||||||
| WBCnstr00011640 | |||||||||
| WBCnstr00037676 | |||||||||
| Construct_product | WBCnstr00008469 | ||||||||
| WBCnstr00008470 | |||||||||
| WBCnstr00008474 | |||||||||
| WBCnstr00008475 | |||||||||
| WBCnstr00011181 | |||||||||
| WBCnstr00011640 | |||||||||
| WBCnstr00037676 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (155) | |||||||||
| Interaction (35) | |||||||||
| Map_info | Map | II | Position | 23.1747 | Error | 0.007585 | |||
| Positive | Positive_clone | F19H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4735 | |||||||
| 5024 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (19) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
