WormBase Tree Display for Gene: WBGene00000165
expand all nodes | collapse all nodes | view schema
WBGene00000165 | SMap | S_parent | Sequence | Y48G8AL | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | aps-3 | Person_evidence | WBPerson360 | |||||
WBPerson567 | |||||||||
Sequence_name | Y48G8AL.14 | ||||||||
Molecular_name | Y48G8AL.14 | ||||||||
Y48G8AL.14.1 | |||||||||
CE30461 | |||||||||
Other_name | apt-8 | Person_evidence | WBPerson625 | ||||||
CELE_Y48G8AL.14 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | aps-3 | ||||||||
DB_info | Database | AceView | gene | 1B628 | |||||
WormQTL | gene | WBGene00000165 | |||||||
WormFlux | gene | WBGene00000165 | |||||||
NDB | locus_tag | CELE_Y48G8AL.14 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000165|UniProtKB=Q8T874 | |||||||
family | PTHR11753 | ||||||||
NCBI | gene | 171691 | |||||||
RefSeq | protein | NM_001392848.1 | |||||||
TREEFAM | TREEFAM_ID | TF300189 | |||||||
TrEMBL | UniProtAcc | Q8T874 | |||||||
UniProt_GCRP | UniProtAcc | Q8T874 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 01 Apr 2005 11:05:24 | WBPerson2970 | Name_change | CGC_name | aps-3 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | aps | ||||||||
Allele (53) | |||||||||
Strain | WBStrain00037857 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00085046 | ||||||||
00085047 | |||||||||
00085048 | |||||||||
00085049 | |||||||||
00085050 | |||||||||
00106919 | |||||||||
Contained_in_operon | CEOP1939 | ||||||||
Ortholog (39) | |||||||||
Paralog | WBGene00000157 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00000159 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | aps-3 encodes an adaptin orthologous to the sigma3 subunit of the heterotetrameric adaptor protein complex 3 (AP-3); by homology, APS-3 is predicted to play a role in intracellular membrane trafficking and specifically, may be involved in transport of lysosomal membrane proteins from tubular sorting endosomes to lysosomes; loss of aps-3 activity via large-scale RNAi screens in the sensitized rrf-3 background indicates that, in C. elegans, APS-3 is required for fertility and reproduction. | Paper_evidence | WBPaper00004907 | |||||
WBPaper00006395 | |||||||||
WBPaper00013401 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 16 Jul 2007 00:00:00 | ||||||||
Automated_description | Predicted to be involved in vesicle-mediated transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human AP3S1 (adaptor related protein complex 3 subunit sigma 1) and AP3S2 (adaptor related protein complex 3 subunit sigma 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | Y48G8AL.14 | |||||||
Corresponding_transcript | Y48G8AL.14.1 | ||||||||
Other_sequence (51) | |||||||||
Associated_feature | WBsf648931 | ||||||||
WBsf663906 | |||||||||
WBsf663907 | |||||||||
WBsf982670 | |||||||||
WBsf1009197 | |||||||||
Experimental_info | RNAi_result | WBRNAi00056965 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00026781 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00116804 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090925 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00026780 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00061008 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00085729 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1027218 | ||||||||
Expr1030094 | |||||||||
Expr1160414 | |||||||||
Expr2009368 | |||||||||
Expr2027604 | |||||||||
Drives_construct | WBCnstr00037693 | ||||||||
Construct_product | WBCnstr00037693 | ||||||||
Microarray_results (16) | |||||||||
Expression_cluster (102) | |||||||||
Interaction (33) | |||||||||
Map_info | Map | I | Position | -16.9364 | Error | 0.002173 | |||
Positive | Positive_clone | Y48G8AL | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00004907 | ||||||||
WBPaper00026639 | |||||||||
WBPaper00029101 | |||||||||
WBPaper00031800 | |||||||||
WBPaper00032502 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00064339 | |||||||||
WBPaper00064934 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |