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WormBase Tree Display for Gene: WBGene00000165

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Name Class

WBGene00000165SMapS_parentSequenceY48G8AL
IdentityVersion2
NameCGC_nameaps-3Person_evidenceWBPerson360
WBPerson567
Sequence_nameY48G8AL.14
Molecular_nameY48G8AL.14
Y48G8AL.14.1
CE30461
Other_nameapt-8Person_evidenceWBPerson625
CELE_Y48G8AL.14Accession_evidenceNDBBX284601
Public_nameaps-3
DB_infoDatabaseAceViewgene1B628
WormQTLgeneWBGene00000165
WormFluxgeneWBGene00000165
NDBlocus_tagCELE_Y48G8AL.14
PanthergeneCAEEL|WormBase=WBGene00000165|UniProtKB=Q8T874
familyPTHR11753
NCBIgene171691
RefSeqproteinNM_001392848.1
TREEFAMTREEFAM_IDTF300189
TrEMBLUniProtAccQ8T874
UniProt_GCRPUniProtAccQ8T874
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
201 Apr 2005 11:05:24WBPerson2970Name_changeCGC_nameaps-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classaps
Allele (53)
StrainWBStrain00037857
RNASeq_FPKM (74)
GO_annotation00085046
00085047
00085048
00085049
00085050
00106919
Contained_in_operonCEOP1939
Ortholog (39)
ParalogWBGene00000157Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000159Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionaps-3 encodes an adaptin orthologous to the sigma3 subunit of the heterotetrameric adaptor protein complex 3 (AP-3); by homology, APS-3 is predicted to play a role in intracellular membrane trafficking and specifically, may be involved in transport of lysosomal membrane proteins from tubular sorting endosomes to lysosomes; loss of aps-3 activity via large-scale RNAi screens in the sensitized rrf-3 background indicates that, in C. elegans, APS-3 is required for fertility and reproduction.Paper_evidenceWBPaper00004907
WBPaper00006395
WBPaper00013401
Curator_confirmedWBPerson1843
Date_last_updated16 Jul 2007 00:00:00
Automated_descriptionPredicted to be involved in vesicle-mediated transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human AP3S1 (adaptor related protein complex 3 subunit sigma 1) and AP3S2 (adaptor related protein complex 3 subunit sigma 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY48G8AL.14
Corresponding_transcriptY48G8AL.14.1
Other_sequence (51)
Associated_featureWBsf648931
WBsf663906
WBsf663907
WBsf982670
WBsf1009197
Experimental_infoRNAi_resultWBRNAi00056965Inferred_automaticallyRNAi_primary
WBRNAi00026781Inferred_automaticallyRNAi_primary
WBRNAi00116804Inferred_automaticallyRNAi_primary
WBRNAi00090925Inferred_automaticallyRNAi_primary
WBRNAi00026780Inferred_automaticallyRNAi_primary
WBRNAi00061008Inferred_automaticallyRNAi_primary
WBRNAi00085729Inferred_automaticallyRNAi_primary
Expr_patternExpr1027218
Expr1030094
Expr1160414
Expr2009368
Expr2027604
Drives_constructWBCnstr00037693
Construct_productWBCnstr00037693
Microarray_results (16)
Expression_cluster (102)
Interaction (33)
Map_infoMapIPosition-16.9364Error0.002173
PositivePositive_cloneY48G8ALInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00004907
WBPaper00026639
WBPaper00029101
WBPaper00031800
WBPaper00032502
WBPaper00038491
WBPaper00055090
WBPaper00064339
WBPaper00064934
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene