WormBase Tree Display for Gene: WBGene00000075
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| WBGene00000075 | SMap | S_parent | Sequence | ZK154 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | adm-4 | Person_evidence | WBPerson493 | |||||
| Sequence_name | ZK154.7 | ||||||||
| Molecular_name | ZK154.7 | ||||||||
| ZK154.7.1 | |||||||||
| CE15265 | |||||||||
| Other_name | CELE_ZK154.7 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | adm-4 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | adm | ||||||||
| Allele (63) | |||||||||
| Strain | WBStrain00001475 | ||||||||
| WBStrain00035664 | |||||||||
| WBStrain00005376 | |||||||||
| WBStrain00050883 | |||||||||
| WBStrain00054921 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00000074 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| WBGene00006804 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| WBGene00006324 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00016423 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019514 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | adm-4 encodes a member of the ADAM (disintegrin plus metalloprotease) family; ADM-4 is highly expressed in most post-embryonic tissues. | Paper_evidence | WBPaper00012790 | |||||
| WBPaper00018171 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Involved in Notch signaling pathway and cell fate specification. Predicted to be located in plasma membrane. Expressed in gonad; hypodermis; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; inflammatory bowel disease; renal fibrosis; and type 2 diabetes mellitus. Is an ortholog of human ADAM17 (ADAM metallopeptidase domain 17). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:195) | ||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:195) | ||||||
| DOID:0050855 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:195) | ||||||
| DOID:0050589 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:195) | ||||||
| Molecular_info | Corresponding_CDS | ZK154.7 | |||||||
| Corresponding_transcript | ZK154.7.1 | ||||||||
| Other_sequence (13) | |||||||||
| Associated_feature | WBsf654167 | ||||||||
| WBsf1005956 | |||||||||
| WBsf1005957 | |||||||||
| WBsf1023311 | |||||||||
| WBsf1023312 | |||||||||
| WBsf237612 | |||||||||
| WBsf237613 | |||||||||
| WBsf237614 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Chronogram510 | ||||||||
| Expr7196 | |||||||||
| Expr12412 | |||||||||
| Expr16262 | |||||||||
| Expr16263 | |||||||||
| Expr1011551 | |||||||||
| Expr1030034 | |||||||||
| Expr1162679 | |||||||||
| Expr2009236 | |||||||||
| Expr2027473 | |||||||||
| Drives_construct | WBCnstr00002345 | ||||||||
| WBCnstr00006179 | |||||||||
| WBCnstr00006180 | |||||||||
| WBCnstr00020872 | |||||||||
| WBCnstr00037749 | |||||||||
| WBCnstr00042866 | |||||||||
| Construct_product | WBCnstr00006179 | ||||||||
| WBCnstr00006180 | |||||||||
| WBCnstr00014416 | |||||||||
| WBCnstr00037749 | |||||||||
| WBCnstr00042867 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (130) | |||||||||
| Interaction | WBInteraction000004517 | ||||||||
| WBInteraction000004518 | |||||||||
| WBInteraction000007023 | |||||||||
| WBInteraction000296157 | |||||||||
| WBInteraction000356278 | |||||||||
| WBInteraction000368037 | |||||||||
| WBInteraction000431396 | |||||||||
| WBInteraction000449136 | |||||||||
| WBInteraction000457617 | |||||||||
| WBInteraction000578948 | |||||||||
| WBProcess | WBbiopr:00000072 | ||||||||
| Map_info | Map | X | Position | -1.20645 | Error | 0.022133 | |||
| Positive | Positive_clone | ZK154 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4144 | |||||||
| 4653 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (20) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
