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WormBase Tree Display for Gene: RGD:621567

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Name Class

RGD:621567IdentityNameCGC_nameAtxn3Inferred_automaticallyAGR_import
Public_nameAtxn3
DB_infoDatabaseRGDid621567
AGRcURIRGD:621567
EnsEMBLENSEMBL_geneIDENSRNOG00000005470
UniProtUniProt_ACO35815
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006446Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionEnables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; histone deacetylase binding activity; and transcription corepressor binding activity. Contributes to histone deacetylase activity. Involved in protein modification process. Predicted to be located in several cellular components, including cytosol; mitochondrion; and nucleus. Predicted to be active in lysosomal membrane. Predicted to colocalize with endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Machado-Joseph disease. Orthologous to human ATXN3 (ataxin 3); PARTICIPATES IN mitochondrial autophagy pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17beta-estradiol; 4,4'-diaminodiphenylmethane; acetamide.Inferred_automaticallyAGR_import