WormBase Tree Display for Gene: RGD:621539
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| RGD:621539 | Identity | Name | CGC_name | Ireb2 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Ireb2 | |||||
| DB_info | Database | RGD | id | 621539 | ||
| AGR | cURI | RGD:621539 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000013271 | ||||
| UniProt | UniProt_AC | Q62751 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00000040 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| OrthoFinder | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| Structured_description | Automated_description | Enables 4 iron, 4 sulfur cluster binding activity; iron-responsive element binding activity; and regulatory region RNA binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; response to hypoxia; and response to iron ion. Located in axon and neuronal cell body. Used to study anemia. Biomarker of anemia; hyperinsulinism; and iron deficiency anemia. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human IREB2 (iron responsive element binding protein 2); PARTICIPATES IN doxorubicin response pathway; iron homeostasis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene. | Inferred_automatically | AGR_import |
