WormBase Tree Display for Gene: RGD:620288
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RGD:620288 | Identity | Name | CGC_name | Calr | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Public_name | Calr | |||||
DB_info | Database | RGD | id | 620288 | ||
AGR | cURI | RGD:620288 | ||||
EnsEMBL | ENSEMBL_geneID | ENSRNOG00000003029 | ||||
UniProt | UniProt_AC | P18418 | ||||
Species | Rattus norvegicus | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00000802 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
Hieranoid | ||||||
Inparanoid | ||||||
OMA | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | Enables several functions, including hormone binding activity; metal ion binding activity; and peptide binding activity. Involved in several processes, including cellular response to electrical stimulus; cellular response to lithium ion; and response to testosterone. Located in several cellular components, including acrosomal vesicle; endoplasmic reticulum; and perinuclear region of cytoplasm. Part of protein-containing complex. Biomarker of vitamin B12 deficiency. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung cancer (multiple); and thrombocytosis. Orthologous to human CALR (calreticulin); PARTICIPATES IN calcium/calcium-mediated signaling pathway; antigen processing and presentation pathway; Chagas disease pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,2,2-tetramine. | Inferred_automatically | AGR_import |