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WormBase Tree Display for Gene: RGD:620288

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Name Class

RGD:620288IdentityNameCGC_nameCalrInferred_automaticallyAGR_import
Public_nameCalr
DB_infoDatabaseRGDid620288
AGRcURIRGD:620288
EnsEMBLENSEMBL_geneIDENSRNOG00000003029
UniProtUniProt_ACP18418
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00000802Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionEnables several functions, including hormone binding activity; metal ion binding activity; and peptide binding activity. Involved in several processes, including cellular response to electrical stimulus; cellular response to lithium ion; and response to testosterone. Located in several cellular components, including acrosomal vesicle; endoplasmic reticulum; and perinuclear region of cytoplasm. Part of protein-containing complex. Biomarker of vitamin B12 deficiency. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung cancer (multiple); and thrombocytosis. Orthologous to human CALR (calreticulin); PARTICIPATES IN calcium/calcium-mediated signaling pathway; antigen processing and presentation pathway; Chagas disease pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,2,2-tetramine.Inferred_automaticallyAGR_import