WormBase Tree Display for Gene: RGD:620106
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RGD:620106 | Identity | Name | CGC_name | Nos1ap | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Public_name | Nos1ap | |||||
DB_info | Database | RGD | id | 620106 | ||
AGR | cURI | RGD:620106 | ||||
EnsEMBL | ENSEMBL_geneID | ENSRNOG00000042929 | ||||
UniProt | UniProt_AC | O54960 | ||||
Species | Rattus norvegicus | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00001116 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
Hieranoid | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | Enables PDZ domain binding activity; enzyme binding activity; and signaling adaptor activity. Involved in neuron projection regeneration; positive regulation of peptidyl-cysteine S-nitrosylation; and regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Located in cytosol and nucleus. Is active in glutamatergic synapse; postsynapse; and presynapse. Colocalizes with nuclear membrane. Used to study depressive disorder. Biomarker of congestive heart failure and sciatic neuropathy. Human ortholog(s) of this gene implicated in nephrotic syndrome type 22. Orthologous to human NOS1AP (nitric oxide synthase 1 adaptor protein); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; all-trans-retinoic acid. | Inferred_automatically | AGR_import |