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WormBase Tree Display for Gene: RGD:620106

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Name Class

RGD:620106IdentityNameCGC_nameNos1apInferred_automaticallyAGR_import
Public_nameNos1ap
DB_infoDatabaseRGDid620106
AGRcURIRGD:620106
EnsEMBLENSEMBL_geneIDENSRNOG00000042929
UniProtUniProt_ACO54960
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00001116Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionEnables PDZ domain binding activity; enzyme binding activity; and signaling adaptor activity. Involved in neuron projection regeneration; positive regulation of peptidyl-cysteine S-nitrosylation; and regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Located in cytosol and nucleus. Is active in glutamatergic synapse; postsynapse; and presynapse. Colocalizes with nuclear membrane. Used to study depressive disorder. Biomarker of congestive heart failure and sciatic neuropathy. Human ortholog(s) of this gene implicated in nephrotic syndrome type 22. Orthologous to human NOS1AP (nitric oxide synthase 1 adaptor protein); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; all-trans-retinoic acid.Inferred_automaticallyAGR_import