WormBase Tree Display for Gene: RGD:3898
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| RGD:3898 | Identity | Name | CGC_name | Tpm1 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Tpm1 | |||||
| DB_info | Database | RGD | id | 3898 | ||
| AGR | cURI | RGD:3898 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000018184 | ||||
| UniProt | UniProt_AC | P04692 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00002978 | Caenorhabditis elegans | From_analysis | Hieranoid | ||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Enables actin filament binding activity; disordered domain specific binding activity; and protein dimerization activity. Involved in several processes, including muscle filament sliding; regulation of actin filament organization; and ruffle organization. Located in actin cytoskeleton. Part of protein-containing complex. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Y; familial hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 3. Orthologous to human TPM1 (tropomyosin 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate. | Inferred_automatically | AGR_import |
