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WormBase Tree Display for Gene: RGD:2862

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Name Class

RGD:2862IdentityNameCGC_nameIdh1Inferred_automaticallyAGR_import
Public_nameIdh1
DB_infoDatabaseRGDid2862
AGRcURIRGD:2862
EnsEMBLENSEMBL_geneIDENSRNOG00000015020
ENSRNOG00065026102
ENSRNOG00060020894
ENSRNOG00055022679
UniProtUniProt_ACP41562
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00010317Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionEnables NADP binding activity and isocitrate dehydrogenase (NADP+) activity. Involved in female gonad development; isocitrate metabolic process; and response to steroid hormone. Located in peroxisome. Human ortholog(s) of this gene implicated in autoimmune disease; hematologic cancer (multiple); hepatocellular clear cell carcinoma; and high grade glioma (multiple). Orthologous to human IDH1 (isocitrate dehydrogenase (NADP(+)) 1); PARTICIPATES IN citric acid cycle pathway; glutathione metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol.Inferred_automaticallyAGR_import