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WormBase Tree Display for Gene: RGD:1307280

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Name Class

RGD:1307280IdentityNameCGC_nameNkx6-2Inferred_automaticallyAGR_import
Public_nameNkx6-2
DB_infoDatabaseRGDid1307280
AGRcURIRGD:1307280
EnsEMBLENSEMBL_geneIDENSRNOG00000017748
UniProtUniProt_ACA6HXC1
D3ZZX2
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00000584Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionPredicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of myelination. Predicted to act upstream of or within several processes, including central nervous system myelination; pancreatic A cell differentiation; and regulation of oligodendrocyte differentiation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spastic ataxia 8. Orthologous to human NKX6-2 (NK6 homeobox 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.Inferred_automaticallyAGR_import