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WormBase Tree Display for Gene: HGNC:8724

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Name Class

HGNC:8724IdentityNameCGC_namePck1Inferred_automaticallyAGR_import
Other_name (13)
Public_namePck1
DB_infoDatabaseHGNCid8724
AGRcURIHGNC:8724
EnsEMBLENSEMBL_geneIDENSG00000124253
UniProtUniProt_ACP35558
DOidDOID:10652
DOID:9352
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00011232Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
WBGene00021043Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import