WormBase Tree Display for Gene: HGNC:8073
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| HGNC:8073 | Identity | Name | CGC_name | Nxf3 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:1354288 | |||||
| TAP-like protein 3 | ||||||
| TAPL-3 | ||||||
| Public_name | Nxf3 | |||||
| DB_info | Database | HGNC | id | 8073 | ||
| AGR | cURI | HGNC:8073 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000147206 | ||||
| UniProt | UniProt_AC | Q9H4D5 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00003835 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| Structured_description | Automated_description | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |
